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Biomedical subjects

S C Poh

Publications and source records attributed to S C Poh.

At least 55 records · Page 3Linked to original sources
PubMed1986

Lung function and respiratory muscle strength after propranolol in thyrotoxicosis.

Thirty-five thyrotoxic patients were assessed before treatment, after treatment with propranolol, and after antithyroid drugs. The first group of patients (n = 17) performed the following tests at all three assessment points: forced expiratory volume in the first second (FEV1), vital capacity (VC), functional residual capacity (FRC), residual volume (RV), total lung capacity (TLC), maximal mid-expiratory flow rate (MMFR), diffusing capacity for carbon monoxide (DLCO), and maximum static inspiratory and expiratory mouth pressures (PImax and PEmax). Arterial blood gas analysis was also performed for the first group of patients. No significant changes were seen either after propranolol or after antithyroid drugs in the FRC, RV, TLC, MMFR, DLCO, or blood gases. The remaining 18 patients, group 2, performed only the FEV1, VC, PImax, and PEmax tests at each assessment. The only index of respiratory function that improved significantly after propranolol was PImax (from 46.5 +/- 16.5 to 53.2 +/- 22 cmH2O, p less than 0.01). This suggests that adrenergic excess may play a role in thyrotoxic inspiratory muscle weakness. After antithyroid drugs, PImax, PEmax, FEV1, and VC all increased significantly as expected.

Adolescent↗
PubMed1986

Systemic to pulmonary artery fistulas in Hodgkin's disease.

A case of Hodgkin's disease with multiple systemic to pulmonary artery fistulas is described. Despite resolution of the parenchymal infiltrate with combination chemotherapy, the vascular abnormalities persisted. Successful closure of the vascular connections occurred after therapeutic embolization with gel foam and alcohol.

Adult↗
PubMed1986

Pulmonary lymphoma or pseudolymphoma: a diagnostic dilemma.

The clinical significance of pulmonary pseudolymphoma remains unresolved. We report a case which highlights the lymphoma versus pseudolymphoma dilemma. An elderly lady followed up for more than ten years with a slowly enlarging right lung mass had on biopsy, lymphoid hyperplasia consistent with a lymphoma or pseudolymphoma. Laboratory investigations revealed hyperglobulinemia due to a biclonal gammopathy with elevated serum immunoglobulin M and G fractions. Monoclonal production of immunoglobulin is today considered more indicative of a neoplasia than a hyperplasia.

Diagnosis, Differential↗
PubMed1985

Noninvasive oximetry in pigmented patients.

Noninvasive oximetry has been shown to be a reliable and convenient way of estimating arterial oxygen saturation. Studies have shown that skin pigmentation did not affect the accuracy of oximetry. However, these studies were performed on healthy subjects and the number studied was small. Our study on 31 pigmented patients in the clinical situation showed that the Biox III oximeter gave readings that closely approximated oxygen saturation measurements from arterial blood (y = 4.75 + 0.93x, r = 0.91, p less than 0.001), confirming the usefulness of noninvasive oximetry even in pigmented patients.

Evaluation Studies as Topic↗
PubMed1983

Myoclonus following severe asthma: clonazepam relieves.

Three cases of severe asthma requiring mechanical ventilatory support after sudden cardiorespiratory collapse developed myoclonus following the hypoxemic insult. They were unable to stand, walk or feed themselves because of these jerky involuntary movements which were worse on intention. Oral clonazepam in varying doses up to 8 mg daily improved the myoclonus remarkably such that they were able to perform these functions unaided.

Adult↗
PubMed1983

Aspergillus epidural abscess in a patient with obstructive airway disease.

A 54-year-old Chinese man with episodic bronchial asthma since 25 years of age was treated for pulmonary tuberculosis in 1976 because of left upper lobe lesions on chest radiograph. In 1981 he presented with an extradural mass compressing the thoracic spinal cord, thought to be tuberculosis but which on biopsy was found to be aspergillosis. Sputum culture, type on skin-prick reactivity and serum precipitating antibodies were positive for Aspergillus. Amphotericin B intravenously, then ketoconazole orally did not substantially improve his clinical course. He died about four months post-laminectomy.

Abscess↗