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Biomedical subjects

S C Moore

Publications and source records attributed to S C Moore.

41 records · Page 3Linked to original sources
PubMedDate not supplied

Prospectively gated cardiac computed tomography.

A fourth-generation scanner has been modified to perform prospectively gated cardiac computed tomography (CT). A computer program monitors the electrocardiogram (ECG) and predicts when to initiate the next scan in a gated series in order to acquire all projection data for a desired phase of the heart cycle. The system has been tested with dogs and has produced cross-sectional images of all phases of the cardiac cycle. Eight to ten scans per series were sufficient to obtain reproducible images of each transverse section in the end-diastolic and end-systolic phases. The radiation dose to the skin was approximately 1.4 cGy per scan. The prospectively gated system is more than twice as efficient as a retrospectively gated system in obtaining complete angular projection data for a 10% heart cycle window. A temporal smoothing technique to suppress reconstruction artifacts due to sorting inconsistent projection data was developed and evaluated. Image noise was reduced by averaging together any overlapping projection data. Prospectively gated cardiac CT has also been used to demonstrate that the error in attenuation measured with a single nongated CT scan through the heart can be as large as 50-60 CT numbers outside the heart in the lung field.

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PubMedDate not supplied

Cardiac computed tomography using redundant-ray prospective gating.

A fourth-generation, computed tomographic (CT) scanner, equipped for prospectively gated cardiac imaging, was modified to control the scan data acquisition by using knowledge of the location of redundant rays in the sinogram. In conventional prospective gating, a computer monitors the electrocardiogram (ECG) and calculates when to initiate the next scan in a gated series in order to acquire all 360 degrees of projection data for a desired phase of the cardiac cycle. However, in each scan of a series, every projection ray is measured twice (when the positions of the source and detector are reversed). Redundant-ray prospective gating takes advantage of this information to improve the efficiency of data acquisition. Using a heart phantom "beating" at 90 min-1, images of all phases of the cardiac cycle with 100-ms temporal resolution were obtained in four scans with redundant-ray gating; whereas a four-scan series with conventional prospective gating yielded worse images of 170-ms resolution.

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PubMedDate not supplied

Prospectively gated cardiac CT. Preliminary results in normal and postinfarction animal models.

Cardiac motion introduces significant artifacts into standard CT images obtained through the heart. A newly developed prospectively gated CT system produced 87 gated scan sets in ten normal and infarcted dogs. Each cycle can provide up to 24 37-70 msec composite images of one transverse slice, equally spaced in time through the cardiac cycle. Eight to 12 2-second scans, obtained during a constant infusion of contrast, were required to collect the data for each gated set. The left and right ventricular myocardium was clearly seen, regions of myocardial infarction were identified, and atrial and ventricular filling and emptying were visualized. In areas of infarction, wall thickness was unchanged from diastole to systole. In addition to improved resolution, a gated CT series evaluation of wall motion abnormalities may provide a better means of locating myocardial infarction than the ungated CT image.

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