Search PubMed⌕ Search

Biomedical subjects

S C Gupta

Publications and source records attributed to S C Gupta.

At least 325 records · Page 18Linked to original sources
PubMedDate not supplied

Morbidity pattern of communicable diseases in an urban area of Uttar Pradesh.

The period prevalence rate of communicable diseases in Uttar Pradesh, India, in the present study was found to be 119.7 per thousand population. There were 1.08 communicable diseases per morbid person. The leading cause of morbidity was ascariasis (24.1 per 1000). The morbidity was significantly higher in young persons (below 14 years of age) and in those without spouse. The social class and educational status were found to have negative association with the morbidity. However, the sex did not show any influence on the morbidity.

Age Factors↗
PubMedDate not supplied

Cold abscess due to malignant pleural mesothelioma.

A middle aged male presented to us with a cold abscess on the left side of chest which later proved to be a malignant pleural mesothelioma. The clinical, radiological and histopathological findings have been discussed.

Biopsy↗
PubMedDate not supplied

Radiological and antroscopic study of maxillary antrum in multibacillary leprosy patients.

Sixty consecutive patients having multibacillary leprosy were examined for symptoms of nasal involvement and sinusitis. A complete ENT examination was carried out of all these patients and they were subjected to radiological examination of paranasal sinuses. Radiological abnormalities of maxillary antrum were found in 15 of 20 cases of lepromatous leprosy, 6 of 26 cases of borderline lepromatous and in 14 cases of mid-borderline leprosy. Localized or generalized mucosal thickening was the most common finding, followed by opacity of maxillary antrum. Radiological abnormalities were confirmed by antroscopy, which is the most appropriate technique for making an accurate diagnosis of maxillary antral diseases. Initially, antral involvement may begin with a localized area of mucol erythema, progressing to a typical granuloma formation and ulceration. The antero-inferior part of the antrum was found to be the most commonly affected region.

Adolescent↗
PubMedDate not supplied

A rapid survey technique for detection of leprosy.

Comparison of prevalence rates of leprosy as assessed by a rapid survey technique, in which only the exposed parts of the body were examined, with that assessed by a routine total body examination in a population of about 700, showed that most cases of leprosy were detected by the former.

Adolescent↗
PubMedDate not supplied

Role of traditional healers and indigenous medical practitioners in health care.

Nearly three-fourth of the indigenous medical practitioners (74.37%) in the rural area of Agra were treating 15 patients in a day. Maximum number of patients was attended by trained practitioners. Only 21.82 percent of the practitioners were providing preventive services apart from curative services. Inspite of wide variations in level of training with consequent difference in knowledge, skills and practice, these practitioners still make a significant contribution to health care of the community provided they get some training of modern health system and state patronage. To start with, at least they should be given orientation towards vaccination as they are still giving tetanus toxoid only at the time of injury. In the same way training should be given regarding distribution of vitamin 'A' for prevention of night blindness and iron folic acid tablets for control of anaemia in vulnerable groups.

Developing Countries↗
PubMedDate not supplied

Antispermatozoal antibodies in leprosy with special reference to their morphological patterns.

Sixty two male patients with polar leprosy--38 lepromatous and 24 tuberculoid types were investigated for the presence of antispermatozoal antibodies with special reference to their morphological patterns. Antibodies were detected by three different immunological techniques. Sperm agglutination was found to be the most sensitive. The incidence of antibodies was higher in patients with lepromatous leprosy and was directly proportional to the duration of the disease in both types of leprosy. Morphologically, head-to-head type of agglutination was observed in 50 percent of the patients, mixed in 41.7 percent and tail-to-tail type in 8.3 percent. There was no correlation between the number of ENL attacks and the incidence of anti-bodies. In polar tuberculoid leprosy patients the histological findings of testicular biopsy indicated cell mediated tissue damage occurring in a non-infective form.

Antibodies↗
PubMedDate not supplied

Serum proteins and immunoglobulins in leprosy.

Serum proteins and immunoglobulins were studied in patients suffering from various types of leprosy. A significant increase in total protein and decrease in albumin was found in all types of leprosy except borderline-tuberculoid. Gamma globulin was found to be increased in all types. An increase of alpha-2-globulin in lepromatous, a decrease of beta globulin in borderline-lepromatous, and a decrease of alpha-2 and increase of beta globulin in borderline-tuberculoid were observed. These changes do not seem to be of diagnostic importance. A statistically significant increase of IgG in borderline-lepromatous and lepromatous, IgM in all types of leprosy and IgA only in lepromatous was found. The increase of different immunoglobulins in leprosy, especially the lepromatous type, suggests a humoral response which was found to be directly proportional to the severity of the lesion.

Blood Proteins↗
PubMedDate not supplied

Carcinogenic effect of 1:3 propane sultone.

Eighty animals were administered propane sultone in either single or multiple doses. The skin lesions at the site of injection were due to necrosis, ulceration, destruction of the underlying muscle and varying grades of fibrosis. In 13 rats pseudosarcomatous changes were seen, the duration of which varied from 21 to 25 weeks after the first injection. Systemic examination revealed neoplastic pulmonary lesions in 17 rats that had been injected with propane sultone 21 to 25 weeks previously. The malignancies varied from adenocarcinoma to anaplastic carcinoma. Malignancy of lungs is here reported for the first time.

Adenocarcinoma↗