Biomedical subjects
Publications and source records attributed to S C Bean.
Management of seizures requires prompt medical attention to prevent morbidity and mortality and to clarify the etiology of the event so that proper long-range therapy can be planned. This article provides an overview of the diagnosis and treatment of this common medical problem.
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Two patients with acute lymphocytic leukemia developed progressive optic nerve and chiasmal lesions eight to nine months after the initiation of identical chemotherapy protocols that included intrathecal medication and prophylactic radiation of only 2,400 rads to the central nervous system. Both patients eventually lost all vision despite additional radiotherapy, and there was no evidence of leukemia involving the central nervous system after acute lymphocytic leukemia was diagnosed. Optic nerve biopsy in one case showed changes consistent with radiation necrosis.
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