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Biomedical subjects

S C Bauserman

Publications and source records attributed to S C Bauserman.

22 records · Page 2Linked to original sources

Sudden death in an infant with central nervous system abnormalities.

Some deaths during the first year of life are classified as sudden infant death syndrome (SIDS), the diagnosis of which requires a complete autopsy without adequate explanation for the death. We report a 1-month-old infant whose clinical history was fairly typical for SIDS. Postmortem examination was remarkable in revealing clinically unsuspected central nervous system (CNS) abnormalities, including lobar holoprosencephaly, absence of the olfactory tracts and grooves (arhinencephaly), subependymal gray matter heterotopias, and delayed myelination. Although the CNS findings do not adequately explain the patient's sudden death, this case illustrates the need for a complete autopsy to include careful CNS evaluation, especially in any presumed SIDS death.

Central Nervous System↗

Intramedullary gliofibroma: MR, ultrasound, and pathologic correlation.

We describe the clinical, MR, ultrasound, and pathologic findings of an intramedullary gliofibroma. This uncommon primitive tumor is thought to be of mixed glial and mesenchymal origin. Although the majority of tumors described to date have been histologically benign, clinical course has been quite variable. On MRI, the tumor we report was isointense to adjacent spinal cord on T1-weighted imaging and became hyperintense on proton and T2-weighted imaging. Enhancement with gadolinium diethylenetriamine pentaacetic acid was mild and slightly heterogeneous. Intraoperative ultrasound demonstrated widening of the lower thoracic cord. Echo pattern was generally similar to that of adjacent cord. The major differential diagnostic considerations include astrocytoma and ependymoma.

Contrast Media↗

Intraventricular fibroma: MR and pathologic comparison.

This case report describes clinical, surgical, MR, and pathologic findings of an intraventricular fibroma, a rare, benign mesenchymal neoplasm. Relatively isointense with normal brain parenchyma on T1-weighted images, the tumor exhibited hyperintense signal on T2-weighted pulse sequences and enhanced intensely and homogeneously after intravenous administration of gadopentetate dimeglumine. Choroid plexus papilloma/carcinoma, meningioma, ependymoma, and subependymal giant cell astrocytoma should be included in the differential diagnosis.

Cerebral Ventricle Neoplasms↗