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Biomedical subjects

S Burton

Publications and source records attributed to S Burton.

65 records · Page 4Linked to original sources
PubMedDate not supplied

An overview of rheumatoid arthritis.

This article aims to inform general nurses about the management of patients with rheumatoid arthritis. It outlines the signs and symptoms, disease processes and treatment, and highlights the importance of the nurse's role in supporting these patients.

Adaptation, Psychological↗
PubMedDate not supplied

Drugs and the eye.

Explore the source record for details and available documents.

Drug-Related Side Effects and Adverse Reactions↗
PubMedDate not supplied

Gene delivery into the renal glomerulus by transfer of genetically engineered, autologous mesangial cells.

To obviate the problem of rejection in situations where cells are used as vectors for gene delivery, the feasibility of using autologous mesangial cells cultured from renal biopsy specimens was studied for the purpose of gene transfer into the glomerulus. Using the calcium-phosphate co-precipitation method, a reporter gene which encodes bacterial beta-galactosidase was introduced into cultured mesangial cells derived from renal biopsy tissue of rats. Stable transfectants were established in the presence of a selection drug and then transferred back into the contralateral kidneys of the same animals via renal artery injection. Among 5 rats tested, expression of beta-galactosidase was detected in the isolated glomeruli from 4 injected kidneys. One week after cell injection, 31 +/- 13% of the glomeruli showed positive X-gal (5-bromo-4-chloro-3-indolyl beta- D-galactopyranoside) staining, indicating expression of the transferred gene. The use of autologous mesangial cells from biopsy specimens is thus realistic and would be useful to obviate the risk of rejection in the mesangial cell vector system.

Animals↗
PubMedDate not supplied

Implementation of collaborative practice through interdisciplinary rounds on a general surgery service.

Interdisciplinary teaching rounds were initiated on a general surgery service at a university teaching hospital. These rounds were designed to promote more efficient patient care by providing an opportunity for enhanced communication among health-care professionals. Improved collaboration is a prerequisite for implementation of critical paths and case management. The authors describe their methods of rounds development and the impact of the rounds on patient outcomes.

Case Management↗