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Biomedical subjects

S Bundino

Publications and source records attributed to S Bundino.

At least 37 records · Page 2Linked to original sources
PubMed1982

Pigmented hidroacanthoma simplex with porocarcinoma. Light and electron microscopic study of a case.

A case of pigmented hidroacanthoma simplex showing malignant transformation into porocarcinoma is reported. Although no intracellular duct formation could be observed as in benign tumors, ultrastructurally the tumor cells showed characteristics similar to those of eccrine poroma. Many melanocytes were seen dispersed within the tumoral nests. The melanocyte-keratinocyte relationship was found similar to that occurring in melanoacanthoma. Porocarcinoma cells showed ultrastructural features similar to those of benign cells.

Adenoma, Sweat Gland↗
PubMed1982

Infantile acropustulosis.

A case of infantile acropustulosis is described. The condition responded to sulfones while it was not affected by any other therapy. Histologically, subcorneal pustules were found; persistent modest eosinophilia and eosinophils were present in the vesicular content, a feature never observed before. The significance of this finding is discussed.

Dapsone↗
PubMed1981

Familial mandibuloacral dysplasia.

A family is described in which two sisters and their two female fifth-cousins were cases of mandibuloacral dysplasia. This syndrome is characterized by mandibular hypoplasia, delayed cranial suture closure, dysplastic clavicles, abbreviated terminal club-shaped phalanges associated with acroosteolysis and atrophy of the skin over hands and feet. Furthermore, in this family alopecia and loss of the lower teeth were noted. We stress the importance of the cutaneous alterations and the possible existence of partial froms of the disease as in one of the patients presented.

Adult↗
PubMed1980

Multiple cutaneous fibromyxomas: a light and electron microscopic study.

A 27-year-old woman developed many nodular lesions, ranging in diameter from 3 mm to 15 mm and clinically indistinguishable from dermatofibromas. Light microscopic examination showed large amounts of mucin, fibroblasts and histiocytes throughout the dermis. Electron microscopic study revealed wide electron lucent areas and long branching winding electron dense threads occupying the ground substance. While dilated cisternae of endoplasmic reticulum containing a finely granular material characterized the fibroblasts, banded structures, intracellular collagen and myelinoid figures were prominent in the histiocytes. The term fibromyxoma is introduced to designate this tumor.

Adult↗
PubMed1980

Disseminated porokeratosis Mibelli treated with RO 10-9359. A study of two cases with ultrastructural remarks.

2 patients with widespread porokeratosis Mibelli (PM) were treated orally with RO 10-9359. The dose was 75 mg/day for 10 days, then 50 mg/day for 3 weeks. The drug produced a good improvement of condition with no serious side effect. Ultrastructural examination of a healed lesion showed the presence of a fine granular substance in the intercellular space of the spinous layer, most likely produced by keratinocytes; ultrastructural cellular alterations of PM were still evident and the lesion recurred after suspension of treatment.

Aged↗
PubMed1979

Dermatofibrosarcoma protuberans. An ultrastructural study of five cases.

An ultrastructural study of five cases of dermatofibrosarcoma protuberans revealed that the basic cell was a spindle shaped fibroblast with a peculiar deeply lobulated nucleus. An origin from perineural and endoneural cells could not be established since basal lamina material was sparsely present in only one case and other differential features were missing. In one case histiocytic cells were found, but also in this case the basic cell was the fibroblast; so evidence of relationship with fibrous histiocytoma was not found.

Adult↗
PubMed1979

Ichthyosis linearis circumflexa Comèl and Netherton's syndrome; an ultrastructural study.

An electron microscopic study of 3 cases of ichthyosis linearis circumflexa Comèl (ILC) reveals the presence of round bodies in the prickle cells: a characteristic feature of ILC. The horny and the granular layers are absent and are replaced by parakeratotic cells with condensed cytoplasm, which an amorphous material dissociates. The early formation of a vesiculopustule is detected. The importance of the dermal inflammation is considered and it is stated that ILC is not a purely epidermal disorder of keratinization.

Adolescent↗
PubMed1978

Dyskeratosis congenita with epidermodysplasia verruciformis of Lewandowsky and Lutz.

The case is reported of a 30-year-old man suffering from dyskeratosis congenita with severe pancytopenia, in association with generalized verrucosis. Viral particles were detected electron microscopically. The importance of an impaired immunological state, demonstrated in this case by lymphocyte stimulation and rosette tests, is discussed.

Adult↗
PubMedDate not supplied

Pityriasis rotunda.

Explore the source record for details and available documents.

Adolescent↗
PubMedDate not supplied

[Clinical evaluation of josamycin in the treatment of acne].

The efficacy of josamycin in the treatment of inflammatory acne has been evaluated in 39 patients. Josamycin was orally administered to the patients as a single 500 mg daily dose for two months, but the patients with the most severe lesions received an initial treatment of 1 g for a maximum of 20 days. All subjects received josamycin in combination with other antiacne drugs mostly benzoyl peroxide ointment. The treatment induced a significant regression of the number and the severity of the lesions scored according to Plewig-Kligman's classification. At the end of the treatment a positive effect was observed for 92% of the subjects, independently of the variety and the degree of the severity of the disease. According to the patients' judgments josamycin was an effective treatment (92.3%) and more effective that the previously prescribed drugs (95%). Only 1 patient reported the occurrence of a side effect (mild gastric discomfort). Josamycin showed in this study to be an effective and safe drug for the treatment of inflammatory acne.

Acne Vulgaris↗