Biomedical subjects
S Bowes
Publications and source records attributed to S Bowes.
Prescribing digoxin in geriatric units--exercise and redistribution of drug.
In subjects capable of normal everyday activity, exercise has been shown to lower the serum digoxin concentration by increasing uptake into skeletal muscle. A randomized cross-over study of the effect on the serum digoxin concentration of treatments consisting of rest for, or exercise during, 30 min was carried out in 20 elderly patients undergoing rehabilitation. In one patient exercise was associated with a marked (40%) reduction in the serum digoxin concentration. In the remainder there was a very small, but statistically significant, fall in concentration in the exercise as compared with the rest period. Unexpectedly low serum digoxin concentrations in in-patients of geriatric units, may occasionally be an artefact due to temporary redistribution of digoxin.
Color preferences in films for fundus photography.
Photographs that provide a colorimetrically faithful image of the original object are known to be subjectively unacceptable. Color photographic films depict a distortion of the color of the original in order to produce a subjectively acceptable reproduction. The distorsions involved may not be appropriate for the reproduction of ocular fundus photographs. This paper assesses the performance of a variety of color slide films in producing photographs of the ocular fundus that are subjectively acceptable. Assessments were made of the photographs of the fundi of blond, dark Asian, and Indian patients. The result of the assessment is a recommendation that points toward the photographic film that will produce the subjectively most acceptable color reproduction.