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Biomedical subjects

S Boucheron

Publications and source records attributed to S Boucheron.

78 records · Page 5Linked to original sources
PubMedDate not supplied

Bronchial carcinoids. A review of 22 cases.

This study investigated 22 patients with histologically proven primary bronchial carcinoids and in particular the relationship between assessment parameters and survival. In each patient, age, sex, smoking habits, mode of presentation, results of diagnostic investigations, methods of treatment and pathological examination of resected specimens were recorded. Follow-up was possible in all patients for at least 5 years. Patients with atypical carcinoids were 10 years older than patients with typical ones. Eleven patients were smokers, all the patients with atypical and 4 patients with typical carcinoid. The most common presenting mode was pneumonia. Fiberoptic bronchoscopy was diagnostic in 11 cases. The survival rate for patients with typical carcinoid was 100%, while it was 57% in patients with atypical carcinoids. Patients with limited disease had a survival of 100%, while in stage III/IV patients showed a lower survival rate (50%). In conclusion, carcinoid tumors of the lung are tumors showing a good prognosis. Five-year survival indicated a significant difference between typical and atypical carcinoids and between limited and extensive disease. A precise staging is recommended for a better treatment and follow-up.

Adolescent↗
PubMedDate not supplied

[Isolated adenocarcinomatous transformation of uterine adenomyosis].

A case of epithelia malignant changes in uterine adenomyosis is reported. The adenocarcinomatous transformation in uterine adenomyosis is rare. It is necessary to identify exactly the lesion to detect several histological tests specially the integrity of endometrium. An initial phase by atypic hyperplasia and the eventual hormonal incidence are considered.

Adenocarcinoma↗
PubMedDate not supplied

[Epidermotropic eccrine carcinoma. Apropos of a case with ultrastructural examination].

Pinkus and Mehregan's epidermotropic eccrine carcinoma shows particular clinico-pathological characteristics which makes it different from the other cutaneous epitheliomas. A case observed on a 81 year old woman is reported. The initial lesion consisted of an ulcerating tumor on the calf, then followed by multiple verrucous papules eruption around it. Within a few weeks, many other verrucous tumors occurred on the upper part of the leg while a lymphedema was developing. One year after the initial lesion has been noticed, the patient died of metastases in distant organs. From a histological point of view, the tumor corresponded to a squamous cell carcinoma that was slightly keratinizing, Bowenoïd epidermotropic, with dermal involvement too. Features of duct formation were identified within solid nests of neoplastic cells, tumor emboli were seen in the lymphatics. The ultra-structural study made it evident that the tonofilaments were precarious in neoplastic cells; the cytoplasm contained glycogen. The inter-cellular bridges and desmosomes were scanty and micro-villi were noted. The latter confirm the sudoral nature of these cells. For Pinkus and Mehregan, this type of tumor originates in the acrosyringium, but we think that a contiguous segment of the sudoral duct must also be probably concerned. The spreading of the epidermotropic eccrine carcinoma occurs in the teguments themselves in a uncommon way. The tumor re-appears from the dermal lymphatic channels. The lymphatic involvement is the main characteristic of this cutaneous carcinoma, verified by metastases existing in distant organs.

Aged↗
PubMedDate not supplied

[Sneddon syndrome: 9 cases].

We observed a series of 9 patients (1 male, 8 females, mean age 49 years) who had experienced cerebral vascular events with livedo racemosa (Sneddon's syndrome). Vascular dementia occurred in 3 patients and in the 6 others there was a single or several acute cerebral ischaemic events. Angiography of the brain revealed multiple distal arterial occlusions in 5 cases and a moya-moya type collateral network in 2. Positivity for anticardiolipid antibodies fluctuated in 4 cases and there was a lupic syndrome in 2. Systemic lupus erythemosus was diagnosed in the last patient. Mitral valve defects were seen in 5 patients, including 3 due to post-rhematitis sequelae which became symptomatic before the appearance of signs of neurocutaneous involvement. Among these three patients, laboratory tests revealed a lupus band in one, anticardilipid antibodies in another and obliterating fibrous endartiritis of the renal arteries in the third. Sneddon's syndrome presents with heterogeneous signs related to its complex pathophysiology.

Antibodies, Anticardiolipin↗