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Biomedical subjects

S Boriani

Publications and source records attributed to S Boriani.

At least 73 records · Page 4Linked to original sources

Spinal lesions due to hyperextension in ankylosing spondylitis.

The authors review the literature and discuss the biomechanical aspects of extension fractures of the spine in ankylosing spondylitis and report 3 cases. They conclude that, although such lesions are rare, patients with ankylosing spondylitis who sustain such trauma must be subjected to thorough radiological examination. The milder lesions have a favourable prognosis, but those involving dislocation are extremely dangerous, both because of the frequent appearance of immediate or delayed medullary complications and because of the high incidence of pseudarthrosis.

Accidents, Home↗

Periosteal chondrosarcoma and periosteal osteosarcoma. Two distinct entities.

This review of 27 cases serves to emphasis that periosteal chondrosarcoma and periosteal osteosarcoma are two distinct entities. Clinically, periosteal chondrosarcoma is less painful than periosteal osteosarcoma and runs a slower course. Radiographically, periosteal chondrosarcoma tends to affect the metaphysis and contains granular or "popcorn" opacities; while periosteal osteosarcoma more often affects the mid-diaphysis and shows lytic lesions with some spicules of reactive bone perpendicular to the underlying cortex. Histologically, periosteal chondrosarcoma shows lobular well-differentiated cartilage with Grade I or II (rarely Grade III) malignancy; periosteal osteosarcoma has a chondroid matrix with some osteoid component and Grade II or III malignancy. The prognosis in periosteal chondrosarcoma is good; conservative surgery is usually effective and metastases are very uncommon. In periosteal osteosarcoma the prognosis is less satisfactory but is better than that of other osteosarcomata; wide surgical excision is, however, needed and the incidence of metastases is about 15 per cent.

Adolescent↗

Acute spontaneous spinal epidural haematoma.

Some aspects of the pathogenesis of acute spinal epidural haematoma are still obscure. However, if the possibility of an iatrogenic lesion is excluded, it must be assumed that there is a congenital or acquired vascular lesion, or else a haemorrhagic diathesis, with minimal trauma or repeated effort acting as a trigger factor. In the vast majority of cases, the syndrome of medullary of cauda equina compression by an acute epidural haematoma has a sudden onset in apparently healthy individuals after a normal amount of effort. In such circumstances the search for predisposing causes can only be speculative. In the present case, there were severe arthrosic changes, whose effect on the dural sac was demonstrable myelographically, but which was previously asymptomatic. Treatment is exclusively surgical. It is effective the earlier it is undertaken. The need for emergency surgery is clearly demonstrated by its inefficacy if delayed for twenty-four hours after the onset of the symptoms.

Acute Disease↗

Exostosis: development, evolution and relationship to malignant degeneration.

The authors report a study of 408 cases of exostosis (318 single and 90 multiple) from the records of the Tumour Centre of the Rizzoli Institute. Special attention was paid to the relationship with peripheral chondrosarcoma, 73 cases of which are also in the records of the Institute, and were separately studied. The authors conclude that it is impossible to determine the incidence of malignant transformation of solitary exostosis. The incidence of malignant transformation of multiple exostoses in the present case material was 13 per cent, but the true incidence would undoubtedly be higher if all patients were followed up for life.

Adolescent↗

Arachnoid cyst.

Arachnoid cyst is a rare cause of cord compression; less than a hundred cases have been found in a critical review of the literature. A case observed personally is reported to illustrate and discuss some special aspects of this syndrome. Some of the characteristics that differentiate it from other cystic formations of the meningeal sheaths are emphasized.

Adult↗

Hemangioendothelioma of bone: a study of 29 cases.

Twenty-nine cases of hemangioendothelioma (H.E.) of the bone have been studied. In addition to the clinical and radiologic features of the tumor, attention was principally paid to the relationships between a tentative histologic grading of malignancy and the clinical course and final outcome of the cases. Three histologic grades are identified: Grade I H.E., Grade II H.E., and Grade III H.E. (or hemangiosarcoma). Grades I and II H.E. are frequently multicentric in the same lower limb. Grade I H.E. has a constantly good prognosis. It may remain stationary for several years even without treatment and it may be cured even by curettage or radiation. Grade II H.E. often has a good prognosis. In one of our cases the initial biopsy was interpreted as being a low grade tumor but the subsequent histology of the local recurrence indicated a Grade III malignancy and the patient died with metastases. Another case was graded II and the patient died with metastases. There are three explanations for this discrepancy: (1) some tumors are malignant in spite of a seemingly low grade histology; (2) low grade and fully malignant areas are present in the same tumor; (3) malignancy may progress in some low grade tumors in the course of time. On the basis of our experience we lean towards the last two possibilities, and therefore recommend histological study of large and multiple sections. Grade III H.E. has a very bad prognosis. The study of H.E. of the bone presents several problems. More information from a larger series of cases is needed to define the value of the histological grading in determining a prognosis, therefore indicating treatment.

Adolescent↗

Brodie's abscess. A study of 181 cases, with special reference to radiographic diagnostic criteria.

A study of 181 cases of Brodie's abscess, in which the diagnosis was histologically confirmed, was made in order to demonstrate radiographic factors common to other conditions, and therefore likely to pose questions of differential diagnosis. Some of the pathological characteristics of Brodie's abscess are described and correlated with the differing radiographic appearances of this inflammatory bone lesion.

Adolescent↗

Resection of the distal end of the radius.

Resection of the distal end of the radius is indicated in the treatment of locally aggressive primary bone tumours, such as giant cell tumour. This requires reconstruction of the resected segment. Various techniques are examined and the one using an autoplastic fibular graft is described in detail. This method preserves good function of the wrist joint.

Arthrodesis↗

Ewing's sarcoma (a review of 195 cases).

The authors discuss their findings resulting from an analysis of a large series (195 cases) of Ewing's sarcoma. In particular they compare the clinical and radiographic pictures and prognosis prior to and after the introduction of adjuvant chemotherapy. This reveals such marked differences in the past and present features of this neoplasm that some of our previous criteria and attitudes to diagnosis and treatment have undergone radical reappraisal.

Adolescent↗

Therapeutic problems in the treatment of cartilaginous tumours of bone.

Two cases of solitary cartilaginous bone tumours are presented. They were slow growing and the radiographs never showed any certain evidence of malignancy. The writers emphasize the difficulties in planning treatment, in view of the tendency towards malignancy shown by these tumours.

Adolescent↗

Leontiasis ossea.

A case of leontiasis ossea, observed over a period of fifty years, is described with particular reference to certain similarities and differences as compared with Paget's disease of bone (osteitis deformans) and fibrous dysplasia. The differential diagnosis is discussed and it is concluded that leontiasis ossea is an entity in its own right.

Adult↗