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Biomedical subjects

S Borgeskov

Publications and source records attributed to S Borgeskov.

At least 37 records · Page 2Linked to original sources
PubMed1984

Perforation of the esophagus. Experience from a department of thoracic surgery.

A series of 39 patients treated for perforation of the esophagus in a department of thoracic surgery is presented and discussed. All but three of the lesions arose from instrumentation within the esophagus. The treatment was mainly operative. There were no deaths among the nine patients with perforation of the cervical esophagus, but the mortality was 63% in the patients with thoracic lesions, partly as a result of frequent presence of serious disease in other organs. The authors stress the importance of more rigorous attention during intra-esophageal instrumentation to early detection and treatment of perforation.

Adult↗
PubMed1984

Bronchopleural leakage treated with fibrin sealant and high-frequency positive-pressure ventilation.

In a 62-year-old man, left spontaneous pneumothorax appeared 14 days after right pneumonectomy. The large air leakage necessitated thoracotomy and resection of a bullous area in the left upper lobe. Pleurectomy was not performed. The air leakage continued for 14 more days until, at a second left thoracotomy, numerous bullae were oversewn and covered with fibrin sealant. High-frequency positive-pressure ventilation (90 respirations/min, 21 l/min) was used for the following 6 hours. After 18 hours there was no more air leakage during spontaneous ventilation and the patient made a good recovery.

Drug Combinations↗
PubMed1983

Endoscopic evaluation at follow-up after Björk tracheostoma.

Fifty-six patients who had had tracheostomy of modified Björk type underwent follow-up examination with tracheal X-ray and endoscopy. In six patients the tracheal lumen was narrowed by one-fourth to one-half. No treatment was required in any case. Endoscopy seems to be the simplest and most reliable method for judging the degree of tracheal stenosis.

Adolescent↗
PubMed1981

A new tracheostomy tube. III. Bronchofiberoptic examination of the trachea after prolonged intubation with the NL tracheostomy tube.

Recent publications show that severe damage to the trachea is still a problem with high-volume, low-pressure cuffs. The NL tracheostomy tube was used in 86 patients for 3 days to 2 months (mean 16 days). This tube has a high-volume, low-pressure cuff with automatic regulation of the cuff pressure at 3 kPa. The tube has a flexible tip. Fiberoptic examination at extubation showed minimal damage to the tracheal mucosa: 33 patients had normal mucosa and the rest had hyperaemia and/or fibrin formation. Four patients had ulcerations from suction catheters and four patients had small, superficial ulcerations produced by the tip of the tube. Of these last four patients, three had skin flaps that exerted pressure on the tube. Severe tracheal damage was prevented due to the combination of automatic regulation of cuff pressure and a flexible tip of the tube.

Bronchoscopes↗
PubMed1980

Changes in serum calcitonin in patients undergoing thyroid surgery.

In order to study the influence of calcitonin as a calcium lowering factor during thyroid surgery, we measured calcitonin, calcium, parathyroid hormone, phosphate and alkaline phosphatases in serum of 10 euthyroid patients undergoing minor thyroid surgery. A significant increase was found in serum calcitonin during the first 48 hours postoperatively (p less than 0.01), as well as a transient decrease in serum calcium ( less than 0.01). Serum parathyroid hormone remained almost constant. The results suggest that the release of calcitonin from the traumatized thyroid tissue is the first step in the development of hypocalcaemia in patients undergoing thyroid surgery rather than an impairment of the parathyroid function.

Adult↗
PubMed1977

Cell proliferation and histologic classification of bronchogenic carcinoma.

The rate of cell proliferation of 99 bronchogenic carcinomas (94 primary tumors and 5 metastases) was evaluated from the labeling index after in vitro incorporation of [3H]thymidine; the rate was then correlated with the histologic tumor type according to the classification of the World Health Organization (WHO). Cell proliferation was significantly slower in adenocarcinoma (WHO type III) than in squamous cell carcinoma (WHO type I), small cell anaplastic carcinoma (WHO type II), and large cell carcinoma (WHO type IV). Cells proliferated at a significantly higher rate in large cell carcinoma than in the squamous cell type, whereas no significant difference was observed between the other cell types. Dedifferentiated forms of squamous cell carcinomas had a higher rate of cell proliferation than did differentiated forms of the same cell type. Metastases of small cell anaplastic carcinoma did not differ in cell proliferation from primary tumors of the same cell type.

Adenocarcinoma↗