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Biomedical subjects

S Bewley

Publications and source records attributed to S Bewley.

57 records · Page 4Linked to original sources

Who defaults after treatment for gonorrhoea? Randomised controlled study of effect of an educational leaflet.

A study of patients with gonorrhoea showed that those who defaulted most from follow up were male, heterosexual, and had multiple sexual partners. A prospective, blind, randomised controlled trial showed that a leaflet giving information about gonorrhoea had a positive effect on follow up attendance by women, but no appreciable effect on rates of defaulting overall. This has implications for the initial treatment schedules.

Adolescent↗

Investigation of the uteroplacental circulation by Doppler ultrasound.

Doppler assessment of the uteroplacental circulation can be performed easily. In early pregnancy, it may identify pregnancies at risk of developing pregnancy-induced hypertension and IUGR. In late pregnancy, a high impedance in the uteroplacental vascular bed indicates that the fetus is at risk of developing hypoxia, but the fetal and umbilical FVW are the best indicators of immediate fetal well-being. Doppler ultrasound also offers the potential for noninvasive experimental hemodynamic studies of the uteroplacental circulation.

Arteries↗

The relationship of uterine and umbilical Doppler resistance to fetal and placental protein synthesis in the second trimester.

The relation of uteroplacental and umbilical Doppler resistance index (RI) to peripheral levels of alphafetoprotein (AFP), human chorionic gonadotrophin (hCG), human placental lactogen (HPL), Schwangerswaft protein (SP1), pregnancy-associated placental protein A (PAPP-A) and insulin-like growth factor binding protein 1 (IGP-BP1) at 16-24 weeks was established in a cross-sectional study of 183 unselected singleton pregnancies. There was an association between high values of uteroplacental RI and high hCG levels, and high umbilical RI values with high hCG and HPL levels. Thus, in the mid-trimester, the levels of some placental proteins seem to be related to placental resistance.

Carrier Proteins↗