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Biomedical subjects

S Betlejewski

Publications and source records attributed to S Betlejewski.

At least 19 recordsLinked to original sources

[Physiology and surgery of the nose].

Understanding the physiology of the normal nasal functions should prevent unnecessary surgery to the septum and turbinates. The most important function of the nose is the respiratory one. Respiration provides oxygen for metabolism and removes carbon dioxide from the body, and it is nose that modifies air so that it is ideal for this purpose. The nose performs three functions: humidification, heat transfer, and filtration. Because of its ability to transfer heat, the nose is very important not only in temperature regulation of the inspired air, but also for the thermal homeostasis of central nervous system. The air flow pattern and the dynamic changes in nasal resistance are significant for heat exchange, for reflexes initiated in the nose and for nasal neurovascular reflexes, therefore all the factors must be taken into account while performing surgery of the nose.

Humans

[Rhinitis medicamentosa: an increasing therapeutical problem].

The most common upper respiratory illness is rhinitis. The majority of ENT specialists and general practitioners prescribe topical decongestants as first line therapy in rhinitis, independently of causes and kind of rhinitis. Long term use of topical vasoconstrictors for the nose may result in rhinitis medicamentosa, the rebound swelling of the nasal mucosa. The swelling probably is due to vasodilatation, but it may be also due to interstitial oedema. The prolonged use of decongestants may destroy the nasal cilia and mitochondria of epithelial cells, disturbing their function. Rhinitis medicamentosa from topical vasoconstrictor abuse results in nasal obstruction which can be life-threatening in neonates. Rhinitis medicamentosa is a increasing therapeutical problem that is best managed by prevention.

Female

[The use of CO2 laser in the treatment of leukoplakia of the oral cavity].

During the period from 1992 to 1996 in the Otolaryngological Clinic of the Medical Academy in Bydgoszcz 20 patients with leucoplakia of the oral cavity were hospitalized. The treatment with the CO2 laser was used. Depending on the kind of lesion single or continuous ray of the power 6-15 W were applied. The patients were divided into 3 groups according to the kind of leucoplakia: patients with simple leucoplakia, patients with nodular leucoplakia, Patients with verrucous leucoplakia. According to the size of the leucoplakia area: lesions of 1 cm diameter, lesions of 2 cm diameter, lesions of over 2 cm diameter were differentiated. In the case of simple leucoplakia the laser ray of 5-6 W power was applied, in nodular leucoplakia 6-10 W, and in verrucous leucoplakia the power was 10-15 W. In this work the results of the 5 years observation are presented.

Carbon Dioxide

[Functional voice evaluation after Reinke's edema treated with CO2 laser and Kleinsasser's microsurgery].

The authors performed functional evaluation of voice in 124 patients treated with microsurgery due to oedema Reincke in the years 1991-1994. In 90 patients surgery was performed with CO2 laser microsurgery and in 34 patients with microlaryngoscopy according to Kleinsasser. The picture of larynx was registered and evaluated with help of laryngovideostroboscopy. The voice status was evaluated in phoniatric examination, registered on tape and submitted to acoustic analysis. No correlation between method of surgical treatment and quality of voice was observed. However, significantly worse quality of voice was noted in those smoking after surgery.

Carbon Dioxide

[The use of the CO2 laser in the treatment of laryngostenosis and tracheostenosis].

The authors show the possibilities of using the laser CO2 in treatment of both laryngostenosis and tracheostenosis in 54 patients. In the article various forms of treatment of laryngostenosis and tracheostenosis as well as the results of the therapy have been presented. On the basis of the cases treated so far, the prospects of using the laser CO2 in this form of treatment have been found limited. The best results have been attained in treating the narrowings on a small surface. In case of complex laryngostenosis and tracheostenosis, the most effective treatment has been obtained by using the combination of the laser microsurgery performed on the larynx area along with the surgical resection of the narrowed segment of the trachea and the fusion "end to end". In some cases good results have been achieved by using the laser CO2 to remove postoperative scars of the larynx after partial laryngectomies.

Aged

[A case of mucous cyst of the nasopharynx].

We presented a rare case mucocele cyst of the nasopharynx in a 41 year old man. The cyst was located at the higher level between the roof and right lateral band of nasopharynx, and was removed by the transpalatal approach.

Adult

[Transcranial Doppler sonography in radical and function neck dissection].

To evaluate the influence of radical or functional neck dissection on cerebral hemodynamics, pre- and postoperatively TCD sonographic examinations were performed in a group of patients following unilateral radical or bilateral radical/functional neck dissection. Cerebral blood flow velocities (cm/s) and pulsatility index (PI) were studied preoperatively and postoperatively 4, 24 and 48 hours after the operation, using a 2 MHz-pulsed transcranial ultrasonographical system (TCD) with a transtemporal approach to the middle cerebral artery. To exclude the influence of general anaesthesia on cerebral circulation TDC was also performed in a group of patients, following operations under general anaesthesia but not radical nor functional neck dissection. The results of both groups were compared with the data obtained in a control group of healthy persons the same age. The reductions in blood flow velocities and concomitant increases in PI observed during the first postoperative insonation in patients after radical/functional neck dissection reflect a heightened resistance to flow in the arterial cerebral vasculature.

Adult

[CO2 laser in treatment of laryngeal carcinoma].

The authors performed functional evaluation of voice in 64 patients, who due to limited carcinoma of larynx were submitted unilateral CO2 laser cordectomy. The appearance and mobility of larynx were registered and evaluated in particular periods post surgery, the patients voices were registered and acoustic analysis submitted. Gradual voice improvement following the wound healing were observed in subjective patients evaluation as in objective one. In some cases very good functional results were obtained, which made possible for patients after CO2 laser cordectomy to continue work requiring good function of larynx.

Adult

[The effect of laryngectomy on the fibrinolysis process in the blood of patients with laryngeal neoplasms].

Some data in the literature indicate on the influence of different kind of surgery on the fibrinolytic process. Tissue plasminogen activator (t-PA) and plasminogen activator inhibitor type 1 (PAI-1)--play important role in regulation of fibrinolysis. The aim of our work was to evaluate the influence of laryngectomy on fibrinolytic potential in the blood of operated patients with larynx carcinoma. Study group consisted of 20 men aged 42-75 years old with larynx carcinoma subjected to total laryngectomy. In the blood of patients we measured the concentration of t-PA:Ag, fibrinogen and FDP levels, PAI-1 activity, and ELT. The increase of t-PA and FDP concentrations, decrease of PAI-1 activity and fibrinogen level with simultaneous ELT shortening indicate on the fibrinolysis activation during the laryngectomy.

Adult

[Epidemiology of malignant neoplasms of the upper respiratory tract and oral cavity in the Bydgoszcz region].

The authors performed epidemiological analysis of malignant neoplasms of the nose, paranasal sinuses, throat, tongue, larynx and salivary glands in Bydgoszcz area. All the patients were treated in the Otolaryngological Clinic of Medical Academy in Bydgoszcz. Patient's sex, age, profession, living and environmental conditions as well as histopathological diagnosis were taken into analysis. The data were referred to various regions of Bydgoszcz province, which were elucidated on the basis of microclimate conditions, industry, soil conditions, density of the forest area, and cultivated agriculture plants. Correlations between occurrence of oral cavity and the upper respiratory tract malignant neoplasms and living conditions as well as kind of profession in different parts of Bydgoszcz province were estimated.

Adult

[Tissue and urokinase plasminogen activators (t-PA, u-PA) and their inhibitor PAI-1 in blood of patients with laryngeal neoplasms].

Plasminogen activators and inhibitors regulate a variety of physiological and pathological processes involved in tissue morphogenesis, cell differentiation, migration, cancer cell invasion and metastasis. Several reports have shown the decrease of fibrinolytic activity in the blood of cancer patients. In this study we measured the concentrations of tissue plasminogen activator (t-PA), urokinase plasminogen activator (u-PA), activity of plasminogen activator inhibitor type 1 (PAI-1) and euglobulin lysis time (ELT) in the blood of 20 men aged 42-75 years old with planoepitheliale larynx carcinoma, and 10 healthy persons in similar age. In this study the mean values of t-PA, u-PA concentrations, PAI-1 activity and ELT in the blood of patients with larynx carcinoma were similar to the examination results of healthy persons, but 40% of our cancer patients have increased activity of PAI-1.

Adult

[Osteosarcoma of the sphenoid bone -- the cause of hemorrhage from the cavernous sinus].

A very rare of the osteosarcoma osteolythicum teleangiectaticum of the paranasal sinuses, treated surgically, is reported. The infiltration and destruction of the sphenoid bone caused a haemorrhage from the cavernous sinus. The difficulties in the preoperative evaluation of the extent of the osteosarcoma in the craniofacial bone structures are discussed.

Cavernous Sinus

[Stellectomy in the treatment of patients with long QT syndrome].

The authors present the surgical technique of stellate ganglion excision as a therapeutic method in patients with the long QT syndrome. The operations were performed through an anterior supraclavicular approach. Discussing the anatomic considerations, the possibilities of complications and side effects, both temporary and permanent, including Horner's syndrome are reviewed. On the base of the review of present literature and the postoperative results in patients treated in the Otolaryngological Department of the Medical Academy in Bydgoszcz, the authors confirm that the results of stellate ganglion excision in patients with the long QT syndrome are encouraging, but the possibilities of complications, including sudden death after stellectomy, must be taken into consideration.

Adult