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Biomedical subjects

S Barton

Publications and source records attributed to S Barton.

124 records · Page 7Linked to original sources
PubMedDate not supplied

HSV-2 specific serology should not be offered routinely to antenatal patients.

The proposal to introduce antenatal screening for HSV has no evidence for a public or individual health benefit; indeed, it has the potential to increase anxiety for patients, with a minimal likelihood of reducing the risk of neonatal herpes infection. Antenatal screening of an essentially healthy population of women must be validated in settings of different rates of neonatal HSV infection and the purposes and limitations of screening clearly outlined. Identification of pregnant women at risk of acquiring genital herpes in pregnancy is also dependent upon being able to obtain the serostatus of the male sexual partner which will reduce the practical application of the test if both patient and partners need to be screened. We recommend that efforts to improve on the currently established mechanisms for reducing the morbidity of neonatal herpes, namely early diagnosis and prompt treatment, must take priority for resources over new and unevaluated screening programmes, such as routine testing of antenatal patients.

Antibodies, Viral↗
PubMedDate not supplied

Psychiatric morbidity in women attending a clinic for vulval problems--is there a higher rate in vulvodynia?

A General Health Questionnaire (GHQ) was completed by 55 women attending a clinic for vulval problems in central London. The GHQ-caseness rate was 40% from which the psychiatric morbidity in the sample was estimated to be 32%. The level of psychiatric morbidity in 10 women with a diagnosis of vulvodynia was similar to that of 41 women with other vulval diagnoses.

Adult↗
PubMedDate not supplied

HIV at the hospital/general practice interface: bridging the communication divide.

Good communication between hospital HIV units and general practitioners is essential if people with HIV are to receive appropriate medical care in the community. However, in the UK the experience of general practitioners looking after people with HIV has been that communication is often inadequate. The reasons for this relate to the way that the HIV epidemic has evolved in the UK and the way that health services providing care in HIV have developed. In this review we will examine the causes of the present situation and suggest ways of improving communication which will have beneficial effects on the care of people with HIV.

Communication↗
PubMedDate not supplied

Oral ganciclovir: a new option for patients with CMV retinitis.

Cytomegalovirus retinitis is a major cause of morbidity in patients with AIDS. The conventional treatment approach has involved insertion of a central venous catheter and intravenous administration of ganciclovir and/or foscarnet. This has been associated with systemic toxicity, line-related sepsis, and implications for patient quality-of-life. An oral formulation of ganciclovir has now been licensed for use as maintenance therapy in CMV retinitis. Multicentred trials comparing oral and intravenous ganciclovir have suggested that although the efficacy may be marginally reduced with the oral formulation, the associated toxicity is significantly lower. With careful and informed decision-making by both clinician and patient, the opportunity exists to enhance the quality of life in this patient group.

Administration, Oral↗
PubMedDate not supplied

Investigating forensic nursing.

Forensic nurses are making a positive impact in our society today. They are reaching out to aid victims of violence by not only attending to their injuries and emotional distress, but also by identifying, collecting, and preserving vital evidence that will be needed to assist their patients to seek justice through the legal system. Misinterpretation or failure to properly obtain evidence may result in a miscarriage of justice. Helping victims obtain validation of their injustice is crucial to their healing process and may be of critical importance in the effort to avoid further victimization. Forensic nurses work with victims of child abuse, elder abuse, domestic violence, sexual assault, and persons involved with violence or imminent death. This area includes psychiatric specialists who intervene not only with victims but also with perpetrators of violent and/or sexual acts.

Adult↗
PubMedDate not supplied

New therapies for the treatment of genital warts.

The treatment of genital warts with cytodestructive agents such as podophyllin and trichloroacetic acid continues to impose a heavy burden on the workload of genitourinary medicine clinics. Consequently clinics are now looking to new, economical treatments that will improve the management of patients with genital warts. The most promising of these new agents is podophyllotoxin, which is now available in pharmaceutically pure form tailored for the home treatment of external genital warts in males and females.

Condylomata Acuminata↗
PubMedDate not supplied

Intralesional vinblastine in the treatment of oral Kaposi's sarcoma.

Kaposi's sarcoma is a common tumour in HIV-infected patients, frequently involving the oropharynx. Conventional treatment with radiotherapy is efficacious, but causes considerable discomfort. This paper illustrates a new technique of local injection of vinblastine into oral lesions, which combines satisfactory palliation with high patient acceptability.

Humans↗