Possible association between radiation exposure and chromosome changes.
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Chromosome Aberrations↗
Biomedical subjects
S Bardhan
Publications and source records attributed to S Bardhan.
Polymorphism in chromosome 4.
Chromosomal analyses were performed on 302 individuals, using QFQ banding techniques to determine the occurrence of heteromorphism of chromosome 4. Two type of heteromorphism were observed, one showing an intensely fluorescent band in the centromere region and the other an intensely fluorescent band in the proximal area of the short arm. No one individual possessed both type of heteromorphism. A higher frequency of chromosome 4 heteromorphism was found in patients with schizophrenia, mental retardation, hyperactivity, developmental delay and speech impediments than in normal individuals.
Adolescent↗
Chdromosome aberrations in mice by the antifungal antibiotic, nystatin.
Nystatin, a fungicide of current medical use, was tested in mice for its effect on chromosomes of bone marrow cells. A significant increase of aberrations, mostly of chromatid type, was observed over a period of from 15 min to 15 days following the application of the drug. Our data indicate a non-random distribution of the breaks.
Animals↗
Spontaneous centric fuscion leading to 2n equals 39 chromosomes in the laboratory mouse.
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Animals↗