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Biomedical subjects

S Bansal

Publications and source records attributed to S Bansal.

At least 91 records · Page 5Linked to original sources

Cavernosography in conjunction with artificial erection for evaluation of venous leakage in impotent men.

Twenty men with incomplete penile erection or inability to maintain an erection were evaluated to determine if venous leakage was a cause. Cavernosography was performed in conjunction with artificial erection induced by infusion of saline into the corpus cavernosa. Thirteen patients requiring higher than normal rates of saline infusion to achieve or maintain erection showed filling of superficial veins in the flaccid state as well as during erection. In five of the seven patients with normal saline requirements there was no filling of superficial veins, and two showed filling in the flaccid state only. Of the thirteen patients whose conditions were diagnosed as venous leakage, seven underwent surgical ligation of superficial veins and deep penile vein arterialization by a saphenous vein bypass graft between the superficial femoral artery and deep penile vein. All these patients had reduced saline requirements postoperatively. When cavernosography is performed in the flaccid state only, filling of superficial veins can occur normally; therefore, these studies should be performed with artificial erection.

Adult↗

Chest pain as a presentation of reactive hypoglycemia.

Reported herein is a patient with multiple hospital admissions for atypical chest pain syndrome who underwent extensive noninvasive and invasive cardiologic testing to exclude ischemic heart disease as an etiology. During one episode of chest pain, the patient was found to have hypoglycemia with a blood sugar level of 46 ml/dl. Two subsequent oral glucose tolerance tests reproduced chest pain during hypoglycemia with values of 47 ml/dl and 27 ml/dl. The patient had previously had no significant clinical response to typical antianginal medications. Following evidence of concurrent hypoglycemia, the chest pain syndrome has significantly decreased with the patient on a low carbohydrate diet.

Coronary Disease↗

Dopamine does not affect parathyroid function in man.

There is conflicting evidence for a role of dopamine (DA) in modulating parathyroid gland function. DA stimulates parathormone (PTH) secretion in cattle in vivo and in vitro, but is without effect on dispersed human parathyroid cells from adenomatous and hyperplastic tissue. Therefore, we studied the PTH response to a 30-min infusion of DA (4 micrograms/kg . min) in five normal male volunteers. There was no change in the levels of PTH, as measured by RIA, although this infusion rate was effective in lowering PRL levels. During the infusion period, total calcium levels remained unchanged. We conclude that, unlike cattle, the parathyroid gland in humans is unresponsive to DA. Thus, the regulation of PTH secretion by biogenic amines has important species variation.

Adult↗

Gross hematuria: a rare manifestation of primary renal candidiasis.

Primary renal candidiasis is an uncommon disorder. It typically presents as urinary tract obstruction secondary to bezoar in the ureter, progressive oliguria (at times alternating with episodes of diuresis), ureteral colic, passage of tissue- or stone-like material, pyuria, and/or progressive renal failure. The patient described here presented with gross and microscopic hematuria. In our literature review, we found neither of these reported as clinical signs of primary renal candidiasis. With the widespread use of drugs (eg, antibiotics, antineoplastic chemotherapeutic agents, systemic corticosteroids) which facilitate the growth of Candida, primary renal candidiasis should be considered in the patient who presents with hematuria.

Aged↗

Bronchoextrapleural fistula after extrapleural pneumonolysis.

This case illustrates the development of a bronchoextrapleural fistula 40 years after extrapleural pneumonolysis with placement of a paraffin pack. The various diagnostic possibilities in the presence of such a radiographic presentation are reviewed.

Aged↗

Haemophilus influenzae tenosynovitis.

A case is reported of polytenosynovitis in a 31-year-old male during the course of a severe bacteraemic illness caused by Haemophilus influenzae type b. The clinical presentation was similar to tenosynovitis caused by bacterial or viral agents. As the management of the H. influenzae tenosynovitis would differ from that due to other causes, the addition of H. influenzae type b to a differential of tenosynovitis should be considered. Recognition and prompt treatment by appropriate antibiotics may be important to avoid suppurative complications affecting the tendons. As the pathophysiology of the tenosynovitis is not clear, careful bacteriological and immunological assessment must be obtained.

Adult↗

Tumoral calcinosis in England.

Two cases of tumoral calcinosis are presented in patients living in England. The clinical and pathological features are described and attention is drawn to the need to consider exotic diseases in patients who have originated from or lived in the tropics.The cause of tumoral calcinosis is not known. It may be a metabolic disease of obscure aetiology but local trauma often appears to be a factor in its development.

Adolescent↗

Comparison of the stability of technetium-labeled peptides to challenge with cysteine.

We have labeled a series of short peptides with technetium-99m either by direct labeling at pH 11 or by exchange from [99mTc]technetium glucoheptonate. Typical labeling yields obtained were as follows: N-acetyl-Gly-Cys(S-Acm)-Gly-Cys(S-Acm)-Gly-NH2 (Acm = acetamidomethyl) 99%, S-benzoyl-mercaptoacetyltriglycine (S-Benzoyl-MAG3) 95%, mercaptoacetyldiglycine-NH2 (MAG2-NH2) 94%, MAG3 92%, N-acetyl-Aib-Aib-Cys-NH2 (Aib = aminoisobutyric acid) 91%, Gly-Gly-Gly-Gly 90%, N-acetyl-Gly-Gly-Cys-Gly 87%, cyclo-1, 4-(Gly-Gly-Gly-Gln) 40%, S-methyl-MAG2-NH2 0%. In the absence of cysteine, all of the labeled peptides were quite stable in solution, with at least 80-90% of the labeled peptide remaining at 24 h. The order of stability of the labeled peptides to challenge with cysteine was found to be MAG3 > S-benzoyl-MAG3 > N-acetyl-Gly-Cys(S-Acm)-Gly-Cys(S-Acm)-Gly-NH2 >N-acetyl-Aib-Aib-Cys-NH2 > MAG2-NH2 > N-acetyl-Gly-Gly-Cys-Gly > cyclo-1,4-(Gly-Gly-Gly-Gln) > Gly-Gly-Gly-Gly. The peptides without a sulfur donor were least stable to challenge with cysteine.

Chelating Agents↗