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Biomedical subjects

S Bando

Publications and source records attributed to S Bando.

At least 37 records · Page 2Linked to original sources
PubMed1990

Significance of T wave abnormality in hypertension studied by spatial velocity electrocardiogram and vectorcardiogram.

The ST-T wave abnormality in hypertension has been considered to be an indicator of poor prognosis, but its precise pathophysiological significance remains unclear. The present study was aimed to correlate the electrocardiographic (ECG) change in T wave and left ventricular characteristics studied by echocardiogram. The T wave abnormality in the ECG represented hypertrophy of the left ventricle or abnormality of systolic function, but it was difficult to differentiate either of them by conventional ECG. It was shown in this study that the anterior displacement of the vectorcardiographic T loop was related to the ventricular hypertrophy and that the abnormal shape or inscription of the T loop was more closely related to the ventricular dysfunction rather than hypertrophy. These results suggested that the vectorcardiogram and spatial velocity electrocardiogram were useful for analysis of the T wave abnormality and add important information in addition to the conventional electrocardiogram.

Aged↗
PubMed1990

[Blast crisis of chronic myelogenous leukemia with blasts expressing both immature B lymphocyte- and myelomonocyte-associated antigens and differentiating into basophils in vitro].

A 43-year-old woman with Ph1-positive chronic myelogenous leukemia (CML) was diagnosed as having blastic crisis. The phenotype of blasts was CD9+, CD10+, CD19+, CD11b+ and CD33+, suggesting the B Lymphoid and myeloid mixed lineage. Two color analysis of CD10 and CD33 revealed that 50% of blast cells had both B lymphocyte- and myelomonocyte-associated surface markers. Rearrangement of the immunoglobulin heavy chain gene was detected. After culturing blasts with 12-o-tetradecanoyl-phorbol 13 acetate (TPA), basophilic granules appeared in cytoplasm of the cells. These granules were positive for toluidine blue staining. This finding that the biphenotypic blasts expressing both B lymphoid and myelomonocytoid features differentiated into basophils suggests that blasts of this case are derived from a common progenitor of B lymphoid and myeloid lineages including basophil.

Adult↗
PubMed1989

[Silent period and initial occlusal sliding time in patients with premature contacts].

This study was designed to examine the relationship between frequency of silent period and initial occlusal sliding time. The subjects consisted of three volunteers with normal occlusal contacts and three patients with premature contacts. Electromyograms of the bilateral masseter muscles, initial occlusal contacts and jaw movements during the habitual tapping (20-25) were synchronously recorded and replayed using Takamatsu's technique. Results were as follows: 1. The frequency of silent period in the bilateral masseter muscles was 95-100% in subjects with normal occlusal contacts and 34-53% in patients with premature contacts. 2. The silent period latency in three normal subjects was 8.9 +/- 1.3 msec in the left masseter and 13.9 +/- 2.2 msec in the right masseter. The silent period latency in three patients with premature contacts was 12.4 +/- 2.6 msec in the left masseter and 13.9 +/- 8.2 msec in the right masseter. 3. The duration of silent period in three normal subjects was 12.4 +/- 2.6 msec in the left masseter and 11.1 +/- 3.7 msec in the right masseter. The duration of silent period in three patients with premature contacts was 9.1 +/- 1.7 msec in the left masseter and 11.1 +/- 5.6 msec in the right masseter. 4. Initial occlusal sliding time in three subjects with normal occlusal contacts was less than 30 msec, and 98% of all slidings lasted for less than 15 msec. Initial occlusal sliding times in patients with premature contacts were distributed between 6 and 80 msec (40%: 6 to 15 msec, 60%: greater than 15 to 80 msec).(ABSTRACT TRUNCATED AT 250 WORDS)

Dental Occlusion, Traumatic↗
PubMed1989

Coronary arteriovenous fistula with vasospastic angina.

A 50-year-old man was admitted to our hospital because of chest pain. Twenty-four-hour ECG recording demonstrated ST-segment depression and elevation at the time of spontaneous angina. During treadmill exercise test, the patient developed chest pain with ST-segment depression in leads V4 to V6. After the administration of nifedipine (10 mg), the patient was able to reach up to the maximum predicted heart rate without anginal symptoms and ST-T changes. Coronary arteriogram demonstrated 50% stenosis at the proximal portion of the left anterior descending artery (LAD) and two small fistulas originated from LAD to pulmonary artery. Spasm was induced at the proximal portion of LAD by the hyperventilation. If patients with coronary arteriovenous fistula (CAVF) have symptoms, elective CAVF ligation has been recommended. However, this case suggests that coronary spasm could be one of the cause of angina pectoris in patients with CAVF. Elective CAVF ligation must be carefully indicated in CAVF patients with angina pectoris.

Angina Pectoris↗
PubMed1989

[Electrophysiological effects of magnesium sulfate on human conduction system].

Electrophysiological studies were performed to evaluate the effects of MgSO4 on human conduction system. Nine patients who received 20 mg/kg of MgSO4 did not show any significant changes in the electrophysiological parameters except for prolongations in the PR and AH intervals. After the infusion of 40 mg/kg of MgSO4 in eleven patients, sinus cycle length and corrected sinus node recovery time were increased but statistically insignificantly. Sinoatrial conduction time, the PR interval and AH interval were increased. The effective refractory period (ERP) of right atrium, ERP of atrioventricular node (AV node), ERP of right ventricule and ERP/QTc were increased significantly. These findings suggests that the antiarrhythmic effects of magnesium were due to (1) suppression of the functions of the sinus and AV nodes, and (2) shortening of the duration of the ventricular vulnerable period during the cardiac cycle and prevention of ventricular arrhythmias related reentry mechanism.

Adolescent↗
PubMed1989

[A case of anomalous origin of right coronary artery from the left sinus of Valsalva with ventricular aneurysm ventricular tachycardia and paroxysmal A-V block].

A 51-year old man was admitted to our hospital, because of syncope. During admission, he had three episodes of syncopal attack. During the episodes, monitor ECG showed two times of ventricular tachycardia and one of paroxysmal A-V block. The left ventriculogram showed dilatation of left ventricle with posterobasal aneurysm, anterobasal and apical hypokinesis. The left coronary artery was normal. The right coronary artery originated from the left sinus of Valsalva and passed through between aortic root and pulmonary trunks. There was no atherosclerotic lesions in both coronary arteries. Non-sustained ventricular tachycardia was induced by triple premature stimulations. The inverse relation between the coupling interval of premature stimulation and the echo interval was recognized. Lidocaine (50 mg IV), Flecainide (300 mg/day), Mexiletine (450 mg/day), and Aprindine (60 mg/day) prevented ventricular tachycardia. Rapid atrial pacing induced paroxysmal A-V block. Permanent pacemaker was implanted because of syncope due to paroxysmal A-V block and ventricular tachycardia was prevented by Aprindine. Recently, the case with anomalous origin of the coronary artery increased by the popularity of coronary angiography. But, this case considered to be rare because of complication with ventricular aneurysm and lethal arrhythmia (ventricular tachycardia and paroxysmal A-V block).

Coronary Vessel Anomalies↗
PubMed1985

Aging changes of riboflavin concentration and glutathione reductase activity in erythrocytes.

Aged erythrocytes obtained by fractionation using gradient centrifugation with Dextran 40, showed lower glutathione reductase activity and riboflavin content than young cells. However, both young and old cells displayed almost the same increase in enzyme activity upon addition of flavin adenine dinucleotide to the test hemolysate in vitro. The lipid peroxide content in the cell membranes showed no consistent changes with aging.

Centrifugation, Density Gradient↗