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Biomedical subjects

S Bahadur

Publications and source records attributed to S Bahadur.

60 records · Page 4Linked to original sources
PubMedDate not supplied

Association of vitamin A, vitamin C and zinc with laryngeal cancer.

BACKGROUND: The incidence of the cancers of the oral cavity, pharynx, esophagus and larynx in different population groups of India is amongst the highest reported in Asian countries. There is evidence that high dietary carotenoids and vitamin C may possibly decrease the risk of laryngeal cancer. Limited data is available from India on the association between these micronutrients and the risk of laryngeal cancer. AIMS: To assess the levels of vitamin A, vitamin C and zinc in laryngeal cancer patients and healthy controls. SETTING AND DESIGN: A hospital based case- control study. MATERIAL AND METHODS: One hundred and fifty five laryngeal cancer patients and a control group of 155 healthy individuals constituted the study population. Individuals in the control group were individually matched with the patients for their age +/- 2 years, sex and place of residence. Venous blood was drawn from the cases and controls and estimations of vitamin A, zinc and vitamin C was done utilizing the standard procedures. STATISTICAL ANALYSIS USED: Paired 't' test to compare the mean serum levels of vitamin A and zinc and plasma vitamin C between laryngeal cancer patients and controls. Univariate logistic regression analysis to calculate the odds ratios and the confidence intervals. RESULTS: The mean serum vitamin A, zinc and plasma vitamin C levels were significantly lower in laryngeal cancer patients as compared to the controls. CONCLUSIONS: The findings of the present study indicated a strong association of these micronutrients with laryngeal cancer in the Indian population.

Adult↗
PubMedDate not supplied

Carcinoma oesophagus in a 14 year old child: report of a case and review of literature.

A 14 year old boy with well differentiated squamous cell carcinoma of the upper oesophagus is being presented because of its rarity. The patient presented with dysphagia for 8 months. Barium swallow and endoscopy revealed a narrowing in the upper oesophagus with a proximal dilatation diverticulum. No definite aetiologic factor could be demonstrated. The case was treated with definitive irradiation with excellent immediate response.

Adolescent↗
PubMedDate not supplied

Preparation and biological activity of some 2-substituted 3-(4'carboxyphenyl)-7-nitro-4 (3H)-quinazolinones.

2-Methyl-7-nitro-3,1-(4H)-benzoxazin-4-one (4) (1) has been treated with various carboalkoxy anilines to furnish 2-methyl-3-(4'carboalkoxyphenyl)-7-nitro-4 (3H)-quinazolinones (1-3). Condensation of 1-3 with aromatic aldehydes yielded 2-styryl-3-(4'carboalkoxyphenyl)7-nitro-4 (3H)-quinazolinones (4-21 except 6). Comp. 17 was the most active one against B. subtilis and S. aurens.

Anti-Bacterial Agents↗