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Biomedical subjects

S B Zanutto

Publications and source records attributed to S B Zanutto.

2 recordsLinked to original sources

Pitch perception in patients with a multi-channel cochlear implant using various pulses width.

Cochlear implants have been designed to partially restore hearing to those people who are totally deaf. Multi-channel cochlear implants offer the opportunity to evoke acoustic perceptions like loudness and pitch, elicited by a controllable pattern of electric stimulation by means of electrodes placed in different places along the cochlear length. In this study, two psychophysical experiments were conducted with 4 patients, 1 prelingually and 3 postlingually-deafened, implanted with the multi-channel cochlear prosthesis Nucleus 22. Experiments were carried out to study the effect of varying the width of the electric biphasic pulsatile stimuli on the discriminative abilities of the pitch perception. The tests involved place pitch ranking and pulse rate discrimination. Place pitch ranking was studied by determining the just noticeable difference in pitch pairs (jnd-pp), defined as the pair of nearest electrodes which elicit different pitch perception. Pulse rate discrimination was studied by determining the just noticeable difference in pulse rate (jnd-pr) defined as the minimal difference in stimulus repetition rate over a given electrode, which elicits different pitch perceptions. Both experiments were conducted using pulses of 400, 200, 100 and 50 microseconds/phase. The results indicated that in spite of the differences in pathologies and personal histories, both jnd-pp and jnd-pr decrease by diminishing the pulse width. Speech perceptual data, measured for various pulse widths, validates the usefulness of decreased pulse width which yields favorable results in the psychophysical tests.

Acoustic Stimulation

Extracochlear electrical stimulation.

Twelve patients with sensorineural hearing loss were stimulated by a transtympanic electrode contacting the cochlear promontory. Nine of them were tested to study hearing perception associated with various features of electrical signals, using an auditory electrical stimulator. Biphasic pulse bursts and sine-wave bursts were used as stimuli. Different electrical characteristics such as amplitude, width and rate for pulses and amplitude and frequency for sine waves were used to investigate hearing perception. The patients' perception threshold, comfortable level, uncomfortable level, dynamic range, just-noticeable difference in frequency or pitch discrimination, just-noticeable difference in intensity or loudness discrimination, loudness perception associated with the electrical signal energy, and sounds associated with electrical stimulation was determined. Pertinent results assisted in the development of a speech electrical stimulator that was used to test three patients for vowel, word, and consonant identification and recognition of patterns of intonation. These results in turn are being used to design a prototype of a single-channel extracochlear prosthesis.

Acoustic Stimulation