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Biomedical subjects

S B Shustov

Publications and source records attributed to S B Shustov.

30 records · Page 2Linked to original sources
PubMed1989

[Hormonal disorders in borderline arterial hypertension].

Measurements of blood plasma ACTH, hydrocortisone, STH, somatostatin, insulin, glucagon levels and plasma renin activity in 70 patients with borderline hypertension (BAH) and in 20 normal male subjects have revealed increased ACTH, hydrocortisone, and somatostatin levels, elevated plasma renin activity, and reduced STH and insulin levels in the patients. A possible role of the pressor hormone system activation in the pathogenesis of borderline arterial hypertension and in BAH transformation into essential hypertension is discussed.

Adolescent↗
PubMedDate not supplied

[State of the endocrine and cardiovascular systems in patients with somatotropin-producing hypophyseal adenoma].

Altogether 16 persons with STH-producing hypophyseal adenoma were investigated by tacho-oscillography, total rheography, blood taken from the ulnar vein, a radioimmunoassay to determine the levels of STH, ACTH, cortisol, deoxycorticosterone, aldosterone, T3, T4, vasopressin, prostaglandin E2, 6-keto-prostaglandin F1 alpha, and plasma renin activity. Acromegalic patients demonstrated an elevated level of STH, and prostaglandin E2 secretion was inhibited. Two groups of patients were singled out according to the hemodynamic state: the 1st group was characterized by a hyperkinetic type of circulation and normotension of borderline hypertension; the 2nd group was characterized by hypokinetic circulation, increased vascular resistance, labile or stable arterial hypertension. The interrelationship of hemodynamic and hormonal indices was unnoticed. It has been assumed that of pathogenetic importance in the development of arterial hypertension is depletion of E2 production, and at early stages--body liquid retention resulting from hypersomatotropinemia.

Adenoma↗
PubMedDate not supplied

[Effect of physical exercise conducted at various times of the day on the regulation of carbohydrate metabolism in patients with diabetes mellitus].

A study was made of the levels of glucose, IRI, STH, ACTH and cortisol in the blood serum (plasma) of 39 patients with diabetes mellitus prior to and after physical exercise testing. 25 patients performed physical exercises on an empty stomach in the morning (8-9 a.m.) 14 patients in the daytime (4-5 p.m.). Exercise therapy in the morning hours resulted in the readjustment of hormonal regulation characterized by the predominance of the activity of the counterinsular systems over the insular one. In the daytime the IRI level in patients with diabetes mellitus increased and the activity of the hypophyseoadrenal system before and after physical exercise testing decreased as compared to morning indices producing a beneficial effect on the carbohydrate metabolic status. Daytime hours seem optimum for exercise therapy of patients with diabetes mellitus of both types.

Adolescent↗
PubMedDate not supplied

[Preparation of physiologically active polymethylmethacrylate on lanthanoid silylamides].

Catalytic activity of silylamide derivatives of three-valent lanthanoids [(Me3Si)2N]3Ln (where Me-CH3; Ln-Pr, Sm, Eu, Gd, Tb, Er, Yb) was studied under conditions of low temperature polymerization of methacrylate. The reaction involved an anion-dependent mechanism and was accompanied by formation of block polymer. The physiological activity of the polymethacrylate produced was manifested as stimulation of the growth rate in bone tissue after its impairments. The organo-element fragment introduced into the polymer was responsible for this kind of activity.

Animals↗