Bilateral Paget's disease of the nipple.
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Breast↗
Biomedical subjects
S B Prasad
Publications and source records attributed to S B Prasad.
Monodermal cystic ovarian teratoma composed of respiratory epithelium.
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Child↗
Vaginal bleeding due to leech.
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Adolescent↗
von Recklinghausen's disease with angiosarcoma in a child.
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Child↗
Primary carcinoid tumour of the testis.
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Carcinoid Tumor↗
Stromal sarcoma of the breast.
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Breast Neoplasms↗
Effect of cis-Dichlorodiammine platinum (II) on surface of tumor & normal cells: biochemical, fluorescence & electron microscopical studies.
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Animals↗
Calcification in ulnar nerve abscess in a patient with leprosy--a case report.
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Abscess↗
Surgical problems of acute onset in leprosy patients and their management in Leprosy Control Programme.
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Adolescent↗
Effect of cis-dichlorodiammine platinum(II) on the agglutinability of tumor and normal cells with concanavalin A and wheat germ agglutinin.
In this paper we report the effect of cis-dichlorodiammine platinum(II) (cis-platin) on the agglutination of normal and transformed lymphocytes with lectins conconavalin A (Con A) and wheat germ agglutinin (WGA) which is a sensitive test to study the expression of cell surface components. Normal splenocytes showed small degree of cell agglutination with Con A and WGA. This cell agglutination of normal splenocytes with these lectins increases significantly after cis-platin treatment at 37 degrees C. The Dalton's lymphoma cells which show a high degree of cell agglutination with Con A and WGA when treated with cis-platin at 37 degrees C results in decrease in the degree of their cell agglutination with these lectins. Agglutination inhibition studies with alpha-methyl-D-glucopyranoside for Con A and N-acetyl-D-glucosamine for WGA shows that this increase and decrease of cell agglutination after platinum treatment of cells is a specific reaction and not non-specific. Incubation of cis-platin treated normal splenocytes with excess of neuraminic acid results in decrease of cell agglutination with both Con A and WGA. cis-Platin treatment of the cells results in the release of sialic acid from the surface of the cells. A correlation between the release of sialic acid from the cell surface and cell agglutination is also discussed.
Animals↗
Ultrastructural & fluorescence microscopical observations on the effect of cis-dichloro-diammine platinum (II) on the surface of tumor & normal cells.
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Animals↗
Use of subtherapeutical dose of cisplatin and vitamin C against murine Dalton's lymphoma.
The antitumor activity of subtherapeutical dose of cisplatin and vitamin C combinations was studied against murine Dalton's lymphoma in vivo. The sequence-dependent synergistic antitumor effect of vitamin C and cisplatin was shown to lead to the regression of the tumor resulting in a significant increase in the host survivals with tumor free hosts. Decrease in tumor pH noted in the treated tumor bearing mice and involvement of host's immune system could be an important step in this sequence-dependent antitumor activity of vitamin C and cisplatin.
Animals↗