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Biomedical subjects

S B Milam

Publications and source records attributed to S B Milam.

42 records · Page 3Linked to original sources

Hypersensitivity to amide local anesthetics? Report of a case.

The majority of adverse reactions to local anesthetics are either the direct result of pharmacologic properties of the local anesthetics and/or vasoconstrictors or the result of excessive anxiety. However, because of the insidious nature of the symptoms, many adverse reactions are mistakenly identified as allergic. The following case illustrates how knowledge of the above and persistence in evaluation can lead to proper classification of adverse reactions to amino-amide local anesthetics.

Amides↗

Extensive bleeding following extractions in a patient undergoing chronic hemodialysis.

A prolonged epistaxis following routine dental extractions was observed in a 50-year-old woman with a history of chronic hemodialysis. Despite the clinical impression of a significant coagulopathy, extensive hematologic testing failed to reveal any abnormalities. Recent evidence suggests that a prostaglandin (prostacyclin) with platelet antiaggregatory properties may be responsible for episodes of prolonged bleeding reported in patients undergoing hemodialysis.

Epistaxis↗

General anesthetics: a comparative review of pharmacodynamics.

General anesthetics, in addition to eliminating the perception of stimuli, profound physiologic effects in other systems including the cardiovascular and respiratory systems. A thorough knowledge of the pharmacodynamics and pharmacokinetics of each agents as well as an understanding of the patient's physiologic reserve will allow the anesthetist to reasonably predict the response to a given drug. The ability to forecast patient responses imparts control over an anesthetic technique which contributes to the overall safety of the procesure. This paper reviews pharmacodynamics of general anesthetic agents commonly used in dentistry

Amnesia↗

Time course of recovery following nitrous oxide administration.

The time course of recovery following a brief exposure to 50% N(2)O in O(2) was assessed using a standard psychomotor test, a subjective ranking of experimental pain, and somatosensory evoked potential recordings. Results of this study suggest that recovery from a brief N(2)O exposure may be prolonged and conventional methods of assessing recovery from CNS active drugs like N(2)O may be inadequate.

Adult↗