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Biomedical subjects

S Asai

Publications and source records attributed to S Asai.

183 records · Page 11Linked to original sources

Incidentally discovered small renal carcinoma: CT and angiography.

CT and angiographic features of nine incidentally discovered small renal adenocarcinomas are reviewed. They were all discovered by CT or US during screening procedures or examinations targeting the liver or pancreas. In our institute, they constituted 56 percent of renal adenocarcinomas whose diameters were 4 cm or less. CT without contrast enhancement detected abnormality in seven of the nine, but two were negative or equivocal. Postcontrast CT delineated all tumors as relatively low-density areas, since the normal parenchyma of the kidney showed intense contrast enhancement. We believe that isodense or nearly isodense masses that show relatively low density after contrast are diagnostic of small solid renal tumors. Dynamic study with a bolus injection of contrast medium added information about the vascularity of the tumors. Angiography revealed hypervascularity in only four of the tumors. The rest were avascular or hypovascular. Four tumors that were avascular in the AP arteriographic view were shown to be hypovascular by a tailored oblique view in which adequate obliquity of the angiographic projection was determined by referring to CT, so that the tumors would be seen in profile and would not be superimposed on by normal parenchyma or vertebral shadows.

Adenocarcinoma↗

MRI of bone marrow.

MRI can visualize bone marrow more clearly than X-CT or RI because the bone generates weak signals whereas the fat in the marrow gives strong signals. We described diagnosis of various bone marrow disorders by MRI technique. Hyperplasia of bone marrow decreased fatty cells and resulted in prolongation of T1, whereas hypoplasia of bone marrow replaced hematopoietic cells with fatty cells and resulted in shortening of T1. In aplastic anemia, the localized hyperplastic areas in abnormal fatty marrow can be visualized. In bone tumor and metastasis to bone marrow, T1-weighted IR image can provide the best contrast between the tumor and normal marrow, although neoplastic and inflammatory lesions can not be differentiated by MRI. In iron storage diseases, MRI can detect early changes by its higher sensitivity to iron than that of X-CT. MRI may be usefull in monitoring bone marrow damages noninvasively to patients under radiation and/or anticancer drug therapy.

Adolescent↗

Radiographic imaging of Pneumocystis carinii pneumonia in patients with acquired immunodeficiency syndrome.

We reviewed the radiographic imaging of Pneumocystis carinii pneumonia in patients with acquired immunodeficiency syndrome to determine the findings of chest radiography, computed tomography, and gallium scintigraphy and to analyze the time course of the resolution of abnormalities on chest radiographs after the initiation of therapy. The patients were one woman and 43 men (mean age, 38 years). After initiation of therapy, the chest radiograph demonstrated deterioration in 36% of patients, rapid improvement in 51%, and no change for the first two weeks in 13%. In 80% of patients, chest radiographs showed improvement within three weeks. On average, the radiographic abnormalities resolved in 45 days. We conclude that chest radiographic abnormalities may appear to have worsened after the initiation of therapy, but most of the follow-up films eventually show improvement.

AIDS-Related Opportunistic Infections↗