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Biomedical subjects

S Antov

Publications and source records attributed to S Antov.

3 recordsLinked to original sources

Does simple hysterectomy alter bowel function?

BACKGROUND AND AIMS: Hysterectomy is believed to be associated with disturbed defecation, mainly constipation. This study longitudinally describes bowel function in women submitted for hysterectomy. MATERIAL AND METHODS: Rectoanal manovolumetry, whole gut transit time and detailed interviews on bowel function and dyspareunia were performed preoperatively and at 3 and 11-18 months after hysterectomy in 42 women. Twenty healthy women matched for age and parity served as manovolumetry controls. RESULTS: No significant changes in anal sphincter pressures could be demonstrated, neither early nor late after hysterectomy. Transit time was unaffected. All but one of the patients claimed that they had been suffering from one or more of the following symptoms; abdominal pain, distension, constipation and dysparenuia. While postoperative interviews revealed a significant improvement with respect to abdominal pain and dyspareunia (P < 0.01) after 3 and 11-18 months, improvement of abdominal distension and constipation proved to be transient only. CONCLUSION: Simple abdominal hysterectomy appears not to interfere adversely with bowel function. On the contrary many patients were relieved from abdominal pain present before operation.

Adult

Gastrointestinal and colonic segmental transit time evaluated by a single abdominal x-ray in healthy subjects and constipated patients.

Gastrointestinal transit time (GITT) and segmental colonic transit times were studied in 56 healthy subjects by repeated daily ingestion of 10 radiopaque markers followed by abdominal x-ray. A seven-day procedure including marker intake for 6 days and a single radiograph on day 7 was found to be a simple method to differentiate between rapid, normal and prolonged transit. Addition of 20 distinguishable markers on day 6 helped to describe transit profiles. Healthy women had longer GITT than men (median 2.4 and 1.9 days, respectively) measured as mean 50% excretion time for the ingested doses of markers. For comparisons with patients percentiles for transit were calculated. In constipated patients the 7-day method demonstrated prolonged GITT as well as transit dysfunction in separate colonic segments. The method seems convenient for clinical use in diagnostic as well as therapeutic studies of colonic transit.

Adult