The Phosphate Metabolism in Fatigued Mammalian Muscle.
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Biomedical subjects
Publications and source records attributed to S Andrews.
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Many accounts of the processing of morphologically complex words have been elaborated within the interactive activation model of word identification. Conceptually, this model adopts a "segmentation-through-recognition" approach to morphological decomposition, which assumes that a complex word activates representations of constituent morphemes as well as the representation of the whole word. However, a detailed consideration of the assumptions of interactive activation frameworks reveals that current implementations of the model are incapable of achieving segmentation-through-recognition.
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Attentional dysfunctions in schizophrenia were investigated using a sentence priming task. Schizophrenic patients and healthy control subjects were presented with sentences to which they were required to make a response based on either semantic or physical stimulus features. Schizophrenics' behavioural responses were slower than those of controls, particularly when attending to semantic relationships, but their performance was no less accurate. Both the P300 and the N400 components of the event-related potentials (ERPs) recorded to the sentence completions were attenuated in the schizophrenic sample. The results are interpreted in terms of a deficit in the active maintenance of semantic information in memory and the integration of new information with this representation.
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A cross-sectional survey was conducted to identify sources of social support for 92 HIV-seropositive mothers and to examine the relationship between social support and initiation of health care after a positive test for HIV antibody. Main outcome measures were self-reported source and amount of social support and length of time between the first positive HIV antibody test and the first visit for HIV care. Results indicated that HIV-infected mothers frequently delay seeking medical care and report attenuated social support networks. A limited program of HIV counseling and testing during pregnancy is unlikely to ensure that they will enter the healthcare system.
To better understand factors associated with symptomatic and asymptomatic vulvovaginal candidiasis, including the role of immune compromise and patient self-report, a cross-sectional analysis of factors associated with the isolation of yeast from vaginal swabs and clinical diagnosis of Candida vaginitis (CV) among 184 HIV-infected women was conducted. Sixty-four (35%) of the women had vaginal swabs positive for yeast. Nineteen (10%) women met the case definition for CV. In a logistic regression model, only CD4 < or = 100 cells/mm3 was predictive of CV (adds ratio = 4.5; 95% confidence interval = 1.0, 20; p = .05). The predictive value of patient self-report of CV was only 12%. This study demonstrates that all HIV-infected women should receive a regular and thorough gynecologic evaluation, regardless of self-reported symptoms. HIV-infected women will benefit from education about prevention and treatment of CV, and women whose CD4 counts are low may wish to consider prophylaxis for CV.
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Increasingly, immediate patient service--whether scheduling an appointment or seeing a physician--is a realistic expectation. Smoothing patient access and hitting service targets takes sophisticated planning and a true scientific approach. The department of medicine at Boston's Children's Hospital has taken a new approach to visit management, using a model that could be applied to any practice in any setting. Staff have set up categories of care and guidelines for scheduling, realigning tasks in order to make better use of provider resources and expertise and restructuring associated supporting operations.
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