Search PubMed⌕ Search

Biomedical subjects

S Andrews

Publications and source records attributed to S Andrews.

At least 73 records · Page 4Linked to original sources

Acquired venous aneurysms.

A case is reported of acquired venous aneurysms in the superficial forearm veins of an oarsman. The aetiology, presentation and complications are discussed.

Adult↗

Appearance of the hymen in newborns.

This study was undertaken to evaluate the genital anatomy of female newborns. Hymenal configuration and the number and location of clefts, bumps, tags, and ridges were observed in 468 neonates; photographs for confirmation were obtained for 449 neonates (96%). Hymenal configurations observed included an annular hymen with a central or ventrally displaced orifice in 80% (372/468) of neonates, a fimbriated hymen in 19% (90/468), and a septated or cribriform hymen in 1% (6/468). Configurations significantly differed by race (P less than .001) but no difference was noted by gestational age or weight. Clefts, which occurred only on the ventral 180 degrees of the rim, were observed in 34% of neonates with an annular hymen. Fifty-six percent of neonates had a longitudinal intravaginal ridge, 87% had an external hymenal ridge, and 13% had a tag extending from the rim or a ridge. Periurethral ligaments were frequently observed. It is concluded that lateral and ventral clefts, intravaginal and external ridges, and periurethral bands are normal anatomical findings in the newborn.

Female↗

Factors affecting the follow-up rate of infants with a hemoglobinopathy trait in a newborn screening and follow-up program.

Multiple factors may contribute to a less than satisfactory follow-up rate of infants with a hemoglobinopathy trait in many newborn screening programs. We retrospectively reviewed the information in a follow-up service of a regional community program in southern Alabama for infants with trait (hemoglobin AS or AC). The follow-up service received the screening results of infants with trait and the mothers' addresses and telephone numbers by two routes: (A) the sickle cell center newborn screening coordinator, for infants born at the university hospital (group A), and (B) the state health department, for infants born in other hospitals in a nine-county region (group B). The follow-up service notified mothers by mail and offered counseling; when no response was received, telephone contact and outreach service followed. From January 1988 through December 1989, 505 infants with trait were referred to the counseling service. Of these infants, 211 were in group A and 294 in group B. The follow-up rate was 78% and 49% in groups A and B, respectively (P less than .001). The mean duration from birth to testing results received by the follow-up service was 27 days for group A and 131 days for group B (P less than .001). Of mothers in groups A and B, 92% and 47%, respectively, resided in the same county where the follow-up service was located (P less than .001).(ABSTRACT TRUNCATED AT 250 WORDS)

Counseling↗

Paired Papanicolaou smears in the evaluation of atypical squamous cells.

Between February 1985 and April 1988, 360 women were seen at Tripler Army Medical Center's cervical clinic as part of a prospective study to assess the value of paired Papanicolaou smears in the follow-up of atypical squamous cells in a cervical cytologic smear. The evaluation consisted of paired repeat Papanicolaou smears and colposcopy. Colposcopically directed biopsies and/or endocervical curettage were performed in 86% of the subjects. The results of the paired Papanicolaou smears were negative/negative in 202 patients (56%). Cervical intraepithelial neoplasia was diagnosed histopathologically in 16% of all patients and in 10% of those with negative/negative repeat smears. We conclude that the presence of atypical squamous cells in a Papanicolaou smear should be considered abnormal and that colposcopy and colposcopically directed biopsies should be performed for these patients.

Adolescent↗

The significance of a negative Papanicolaou smear with hyperkeratosis or parakeratosis.

The significance of a cytologic diagnosis of hyperkeratosis or parakeratosis on a Papanicolaou smear reported as negative is unknown. We conducted a review of 170 women without uterine descensus who presented to Tripler Army Medical Center cervical clinic with a negative Papanicolaou smear but with hyperkeratosis or parakeratosis noted on the slide. All patients underwent colposcopy, and 64% had either cervical punch biopsy or endocervical curettage. Six women (3.5%) had cervical intraepithelial neoplasia documented histopathologically. We conclude that the cellular findings of hyperkeratosis or parakeratosis on a Papanicolaou smear are not associated with an increased histologic or colposcopic detection of cervical intraepithelial neoplasia.

Adolescent↗

Patterns of psychiatric morbidity in a genito-urinary clinic. A validation of the Hospital Anxiety Depression scale (HAD).

The prevalence of psychiatric disorder (by DSM-III criteria) in a population attending a genito-urinary clinic was found to be 31%. The performance of the Hospital Anxiety Depression (HAD) scale as a screening questionnaire for psychiatric disorder was assessed. Case definition by a score of 8 or more on either of the anxiety or depressive subscales produced optimal results, giving sensitivities of 82% and 70%, and specificities of 94% and 68%, for depressive and anxiety disorders respectively.

Adult↗

Bacteriophages associated with multiresistant Staphylococcus aureus in Australia.

Nineteen multiresistant strains of Staphylococcus aureus from Australian hospitals were examined for lysogenic bacteriophage. Thirteen strains contained prophage inducible with mitomycin C. Three of these lysed completely on induction producing a phage referred to as type 1; this phage plated on S. aureus propagating strains 6, 53 and 77, which are hosts for phages of serogroup-lysogroup A III, B III and F III respectively. Type-1 phage did not plate on other propagating strains representative of the other serogroup-lysogroup combinations in the International Typing Set for S. aureus. Ten strains of S. aureus lysed incompletely when treated with mitomycin C, yielding phage type 2, that plated only on propagating strain 6. The virions of phage types 1 and 2 had isometric heads and flexible tails, and the genome consisted of c. 40 kilobases of double stranded DNA. The DNA from the two phage types was different, as shown by endonuclease digestion and by hybridisation to reference phage DNAs. The remaining six S. aureus strains contained no phage inducible with either mitomycin C or ultraviolet irradiation. However, all contained type 2 DNA, as shown by Southern blotting, present presumably in a defective prophage state. Moreover, the three strains yielding type-1 phage on induction also contained type-2 DNA. Thus, type-2 DNA was found in all 19 strains of multiresistant S. aureus from geographically diverse Australian hospitals.

Australia↗

Selective medium for isolation of Fusarium species and dematiaceous hyphomycetes from cereals.

A selective medium containing 2 micrograms of dichloran per ml, 200 micrograms of chloramphenicol per ml, and 1.5% bacteriological peptone was developed for the isolation of Fusarium species and dematiaceous hyphomycetes from cereals. The medium, designated DCPA, was shown to select against species of Aspergillus, Penicillium, Cladosporium, and mucoraceous fungi. DCPA was evaluated for use as an enumeration medium and compared satisfactorily with dichloran-rose bengal-chloramphenicol agar when both media were tested with a range of cereal samples. Fusarium species and dematiaceous hyphomycetes produced well-formed colonies with good conidial production on DCPA, permitting rapid identification of such isolates on this medium.

Aniline Compounds↗

Patient-therapist mismatch: we would rather switch than fight.

The authors studied 21 psychiatric outpatients who were granted a change in therapist at their request. The study sample did not differ significantly from other outpatients in demographic characteristics or diagnosis. Results indicated that the great majority of requests for a change in therapists resulted from patient-therapist mismatch, and the majority of patients who changed therapists remained in treatment with the new therapist and reported being satisfied with the change. The authors believe that a flexible policy regarding changes in therapists will enhance treatment effectiveness, and they offer suggestions on how to manage transfers.

Adult↗

A survey of practising psychiatrists' views on the treatment of schizophrenia.

Practicing psychiatrists' views about the treatment of schizophrenia were investigated as part of a Quality Assurance Project. A questionnaire which asked for treatment recommendations for each of four case descriptions of patients with schizophrenia was mailed to a one-in-six random sample of Australian psychiatrists; 90% responded. Psychiatrists almost uniformly advocated the use of antipsychotic drugs and usually recommended concurrent supportive psychotherapy or family/social intervention procedures. The recommendations varied systematically, according to the initial history obtained and to the initial response to treatment.

Attitude of Health Personnel↗