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Biomedical subjects

S Anderson

Publications and source records attributed to S Anderson.

640 records · Page 36Linked to original sources

Traditional maternity care within a bio-social framework.

This study, using quantitative and qualitative methodologies attempts to draw a profile of traditional midwives in Botswana through describing their demographic characteristics, the patterns of communication between midwives and patients, their knowledge and practices and their cooperation with the modern maternity care sector. From the case study emerges a profile of a traditional midwife who: is socially and culturally integrated in the local community; represents a highly valuable source of information on cultural conceptions of crucial importance to childbearing Botswana women; demonstrates the value of a close personal interaction and communication with the pregnant and delivering woman; realizes the limitations of her own capability in birthing situations; and maintains a close communication with the local hospital to which she refers patients when required. The traditional midwife described in this case study is probably not a prototype of the contemporary Motswana traditional midwife. However, she does represent many of the valuable characteristics of the traditional approach which we in the modern sector might benefit from studying in order to improve the human quality of our own care. On the basis of this and other studies, it is recommended that cooperation be developed between modern and traditional midwives, not with the intention of controlling or regulating, but to respect the unique character of each. It appears that an open-minded cooperation between two independent sectors providing health care to the childbearing population is the optimal choice for the country at the present time. A policy for the structured cooperation between the two sectors might include the following: Regional education seminars for both modern and traditional midwives.(ABSTRACT TRUNCATED AT 250 WORDS)

Botswana↗

Community responses to AIDS.

As it becomes clear that national actions alone will not handle the AIDS epidemic, more responsibility is being given to communities, whose characteristics lend themselves to coping with the complicated aspects of the AIDS epidemic. But community members cannot handle the AIDS-related problems alone. They need help in overcoming the fear and stigma; bridging the geographical distances; confronting the double trouble of HIV and TB; and sharing the disproportionate burden of care on women. Below, community responses to AIDS in Africa and some lessons learned.

Africa↗

The University of Maryland experience in integrating preventive medicine into the clinical medicine curriculum.

Lifestyle risk factors play a major role in the etiology of premature mortality, morbidity, and disability in the United States. Numerous professional groups as well as the Surgeon General of the Public Health Service have recommended that increased attention be devoted to training medical students and physicians to improve their knowledge and skills in health promotion and disease prevention. Such training is critical for attaining many of the "Healthy People 2000" objectives. For a variety of reasons, however, most medical schools have had difficulty in successfully integrating preventive medicine into their clinical curriculums. This article describes the critical elements that allowed the faculty at the University of Maryland School of Medicine to accomplish this goal through its fourth year clinical preventive medicine course. The strategies employed in this course may serve as a model for other institutions to achieve the integration of preventive medicine into their clinical curriculums.

Adult↗

Phosphorothioated antisense c-myc oligonucleotide inhibits the growth of human colon carcinoma cells.

BACKGROUND: The functional significance of c-myc overexpression in human colon carcinoma is unclear. MATERIALS AND METHODS: Three human colon carcinoma cell lines, LS174T, SW1116 and SW48, were treated in vitro with phosphorothioate modified antisense oligonucleotides (ASO), complementary to the c-myc translation initiation site, or two control oligonucleotides. Growth was assayed by the methyl tetrazolium (MTT) assay and colony formation. C-myc, retinoblastoma (Rb), carcinoembryonic antigen (CEA), and alkaline phosphatase (AP) expression was assessed by immunoblotting. RESULTS: The ASO specifically inhibited growth of all three human colon carcinoma cell lines. Further studies were conducted on LS174T because growth inhibition was associated with a more differentiated morphology. In LS174T cells, ASO caused a dose dependent decrease in c-myc and Rb protein expression, but an increase in CEA and AP expression. CONCLUSIONS: The growth of human colon carcinoma cells is dependent on c-myc expression, and the inhibition of c-myc expression in LS174T is associated with a more differentiated phenotype.

Alkaline Phosphatase↗