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Biomedical subjects

S Amati

Publications and source records attributed to S Amati.

26 records · Page 2Linked to original sources

Particular aspects of seminiferous tubules at early puberty.

In the seminiferous tubules of patients at early puberty we have observed Sertoli cells showing an homogeneous aspect. In the cytoplasm of some of these elements dense bodies, which present a particular structure and shape, have been recognized. As far as the germ cells, we can find spermatogonia, spermatocytes and spermatids at various developmental stages. The presence of intercellular bridges among the germ cells and of binucleated spermatids with only one acrosome is a characteristic and fairly frequent finding in our specimens, obtained from normal patients.

Adolescent↗

Further contributions about the use of the horseradish peroxidase (HRP) in the ultrastructural study of the olivary neurons of cat.

In order to recognize with E.M. the specific aspect of HRP in olivary neurons of cat, we have used newborn animals twenty-four, forty-eight hours old. The observation of these neurons has allowed us to see a numerous series of dense bodies various in size and density; these bodies have never been found in similar neurons from adult cats or from newborn cats not treated with HRP. These structures could represent the equivalent of an intraneuronal storage of enzyme, whose presence had been confirmed by O.M.

Animals↗

The retrograde transport of horseradish peroxidase: problems in the interpretation of its ultrastructural aspects.

In this study we consider critically the use of HRP in research on the ultrastructure of the Central Nervous System. In fact, although controls make by optical microscope on semi-thin sections made us certain that some of the neurons were definitely marked with the enzyme, when the same specimen was observed by electron microscope, in no case was it possible for us to distinguish any particular aspect of the ultrastructural morphology of labelling within neurons.

Animals↗

Ultrastructural aspects of Sertoli cells in infancy.

In the present study some aspects of Sertoli cells of testicular-biopsy specimens of children from 0 to 8 years old are examined. We can distinguish two main morphological situations. In the first one, Sertoli cells with monomorphic aspect can be seen; in the second can be shown Sertoli cells with various aspects. In this polimorphic situation we can distinguish three Sertoli cell types differing in cellular shape, cytoplasme electron-density and amount of RER and Golgi complex.

Biopsy↗

[Particular ultrastructural aspects of human Paneth's cells].

Our research is about the ultrastructural aspects of Paneth cells obtained from human jejunal mucosa. The cells appear columnar in shape and show a roundish nucleus; their cytoplasm is characterized by a great amount of R.E.R. and by typical large granules in sopranuclear position. Our results confirm those previously described by other authors about the morphology of Paneth cells. In our specimens we have found moreover a variable number of particular cytoplasmic structures; these may show a fibrillar or granular matrix and are always surrounded by a membrane.

Cell Nucleus↗

Chronic obstructive pulmonary disease and associated patterns of memory decline.

The relationship between chronic obstructive pulmonary disease (COPD) and cognitive functioning was analyzed in a study with 50 aging patients. A complex pattern of interactions was identified between emotional and cognitive functioning and chronic respiratory disease when the effects of age, sex, type and severity of disease were controlled. These patients did not show any global and diffuse cognitive impairment. Only a portion of COPD patients (about 30%) evidenced memory impairment which was confined to immediate memory. Memory impairment found in these patients did not appear to be associated with those changes present in the aging process but was mainly related to those specific clinical and instrumental parameters which are considered valid indicators of respiratory efficiency. Two types of cognitive and emotional problems were identified. A progressive stage-dependent set of characteristics was associated with the course of the disease and a fluctuating, probably reversible state-dependent set of characteristics was associated with the temporary condition of the patients during the period of examination. Patients who had received more recent medical treatment or who were under protection of vaccination for influenza showed a better cognitive and emotional efficiency.

Aged↗