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Biomedical subjects

S Alexandru

Publications and source records attributed to S Alexandru.

At least 19 recordsLinked to original sources
PubMed1977

[Neuropsychological investigations of thought processes in aphasics (author's transl)].

Fifteen aphasics and 10 patients with cortical lesions of the right (nondominant) hemisphere were examined using 10 nonverbal psychological tests with 23 variants. The number of correct solutions and the duration of fulfillment of each variant were recorded with statistical significance and standard deviations. Aphasics as well as patients with right-sided cortical damage have lower scores than normal individuals for both correctness and duration of performance. The two groups of patients differed in that the number of correct solutions was higher in aphasics than it was in right-sided cortical injury cases. Aphasics required a longer time to perform the tests used by the authors than normals did, and those with right-sided cortical lesions required an even longer time. The results were also dependent on the kind of test applied. For example, the differences shown by tests 4, 5, 6, and 10 were comparatively less among the three groups (normals, aphasics, and right-sided damage of the cortex) and nonsignificant. The results are discussed in relation to thought processes, language, and aphasia.

Accidents, Traffic↗
PubMedDate not supplied

Comparison between reverse transcription-polymerase chain reaction and immune enzyme assays in the diagnosis of hepatitis C virus infection.

This is the first study of HCV infection performed in Romania by reverse transcription-polymerase chain reaction (RT-PCR). We set up our own protocol, using "nested" primers located in the 5' UTR of HCV. Thirty two patients, 16 with chronic hepatitis, 7 with hepatic cirrhosis and 9 without chronic hepatic disease were investigated. The assignment of each patient to one of the groups was based on clinical and laboratory criteria, especially transaminase levels and hepatic biopsy findings. In 14 out of 16 (87.5%) chronic hepatitis cases and in 6 cases of hepatic cirrhosis out of 7 (85.7%), there was good agreement between RT-PCR and ELISA results. Transaminase levels were concordant with RT-PCR results in 27 of 29 cases (93.1%) but in only 21 of 29 cases (72.4%) transaminase levels were in agreement with ELISA results. In two patients treated with interferon, transaminase levels and the other clinical and laboratory parameters fell in the normal range in parallel with the disappearance of viremia, whereas anti-HCV antibodies were still detectable. RT-PCR has a higher specificity in detecting the etiology of hepatic diseases if compared to ELISA and an at least equal sensitivity. The method proves to be the best means for the confirmation of HCV infection, and for the monitoring of interferon therapy.

Antisense Elements (Genetics)↗
PubMedDate not supplied

[20 years of experience in the use of radiophotography in the prevention of tuberculosis].

Based on a 20 years experience in the application of the pulmonary radiological control relying on radiophotography, the authors reached the following conclusions: -- 40% of subjects considered as suspect following radiophotography were confirmed to have pathological thoracic changes of which 8.5% with acitve pulmonary tuberculosis; in 1954 60% new cases were detected with 73% early forms of the disease and in 1973, 85% of new cases with 90% early forms of the disease; the effects of annual integral radiophotographic defection, correlated with other forms of anti-tuberculous fight, can be expressed in the following morbidity data : in 1954 -- 1.400.000 ; in 1956 -- 870.000 ; in 1957 -- 300.000 ; in 1962 -- 170.000 ; in 1963 -- 80.000 ; in 1966 -- 50.000. This last figure was maintained until 1969, two small increases being noted in the following two years (1970 and 1971). In the last year (1973) the figure was 40.000.

Humans↗
PubMedDate not supplied

[Contribution of medical radiophotography in detection of non-tubercular intrathoracic diseases].

Concomittantly with the reduction of the tuberculous processes and with the transfer of the patients to pneumology sections radiophotographical detection of other pulmonary diseases has become more important. From the control of suspects the following data could be obtained: 8.5% cases of active tuberculosis, 21.46% cases with minimal lesions and with sequellae, 7,2% non-specific pneumopathies, 1.10% cardiovascular patients, 0.23% pleuro-pulmonary tumours and 0.51% cases with other affections.

Evaluation Studies as Topic↗