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Biomedical subjects

S Alexander

Publications and source records attributed to S Alexander.

At least 235 records · Page 13Linked to original sources
PubMed1975

Ureteroileosigmoidostomy. Long-term results.

Ureteroileosigmoidostomy has been performed on 86 patients during the past twenty years, primarily for carcinoma of the bladder. Twenty-seven patients survived longer than five years. Severe complications occurred in 25 cases, and 11 per cent of the series required subsequent surgery. Hydronephrosis developed in 10 per cent. Ureteral reflux could be demonstrated by diatrizoate meglumine (Gastrografin) enema in 6 patients only.

Acidosis↗
PubMed1975

On the immunology of head and neck cancer--a prognostic index. Preliminary communication.

A pilot study on the immune response in patients with carcinoma of the head and neck has been made. The clinical behaviour of such neoplasia is reasoned as being partly determined by the immunological response. If prognosis is related to competence of the immune system then this parameter should be assessed. DNCB (di-nitro-chloro-benzene) skin sensitization and serial lymphocyte transformation studies were performed on all patients whose progress was studied for at least two years. On analysing the results of survival, patients could be divided into two groups--DNCB positive and DNCB negative. The negative patients could be further subdivided; those with a lymphocyte stimulation index of over fifteen; and those beneath this level--the former had a much better prognosis than the latter. Also, such cancer patients were shown to have both cellular and serum factors causing depression of lymphocyte transformation. In the light of all findings, a future programme of investigation is proposed.

Antibody Formation↗
PubMed1975

Phenylbutazone and hepatitis.

During a comparative trial between enteric-coated and rectally administered phenylbutazone in patients with rheumatoid disease, one patient developed a mild hepatitis. She had recently concluded a long period of gold therapy. The natural history of phenylbutazone hepatitis is reviewed on the basis of 41 case histories, and the experience with this individual patient interpreted accordingly.

Aged↗