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Biomedical subjects

S Albert

Publications and source records attributed to S Albert.

115 records · Page 7Linked to original sources
PubMedDate not supplied

Six enteropathogens isolated from a case of acute gastroenteritis.

Isolation of six different gastrointestinal pathogens (Entamoeba histolytica, Plesiomonas shigelloides, Campylobacter jejuni and three different Salmonella species [Salmonella typhimurium, Salmonella blockley and Salmonella hadar]) in the feces of a German female tourist suffering from acute diarrhoea after a trip to Bali.

Acute Disease↗
PubMedDate not supplied

Msb4p, a protein involved in Cdc42p-dependent organization of the actin cytoskeleton, is a Ypt/Rab-specific GAP.

Ypt/Rab proteins of the Ras superfamily are regulators of protein transport in exo- and endocytosis. Like Ras and Rho proteins, they have a slow intrinsic GTPase activity that can be accelerated by several orders of magnitude by GTPase-activating proteins (GAP). Here we describe a new member of a family of Ypt/Rab-specific GAPs, Msb4p/Gyp4p, that shares with other Gyp family members significant homology in the catalytic domain, recently identified in Gyp1p and Gyp7p. Purified Msb4p/Gyp4p acts primarily on Sec4p, Ypt6p and Ypt7p and might have a role in polarized secretion.

Actins↗
PubMedDate not supplied

Effect of custom orthotics on plantar pressure distribution in the pronated diabetic foot.

The F-scan system was used to study plantar foot pressure in patients with a pronated foot type. Inshoe measurements were made under the first metatarsal head and medial heel with and without an orthotic in an extra depth shoe. The F-scan system was also used to compare the total contact area under the foot between each patient with and without the orthotic device. Data collected in this study demonstrated a reduced plantar pressure under the first metatarsal head and medial heel in the patients with an orthotic (30-40% reduction). Calculations of the total contact area under the foot revealed an increase in contact area with an orthotic in extra depth shoes (5-10% increase). Pressure-sensitive insoles, which were replaced as needed, provided reproducible measurements of dynamic plantar pressure and contact area through repeated measurements over the 3-month period of this study. Evaluations show that a custom-made foot orthotic can increase total contact area (redistribute force) and is able to reduce plantar pressures. Thus, an orthotic should reduce the risk of ulceration in the diabetic neuropathic foot.

Aged↗