Search PubMed⌕ Search

Biomedical subjects

S Agarwal

Publications and source records attributed to S Agarwal.

At least 307 records · Page 17Linked to original sources
PubMed1987

Rhabdomyolysis in the patient undergoing head and neck surgery.

Rhabdomyolysis is increasingly recognized as a cause of acute renal failure. Though often the result of extensive trauma, rhabdomyolysis may also appear in the postoperative period. We describe three recent cases in patients undergoing head and neck surgery. Early diagnosis is based on laboratory and clinical examination. Treatment aimed at renal hyperperfusion with hydration and diuretics may prevent nephrotoxic reaction.

Adult↗
PubMed1987

Spontaneous release of malondialdehyde from ultraviolet light exposed liposomal membranes.

UV absorption spectroscopy revealed the presence of MDA with characteristic maximum at about 266 nm in the dialysate of the UV irradiated liposomal suspension. The amount of MDA released increased linearly with increasing UV dose. The fluorescence method for the assay of MDA was found nearly 1500-fold more sensitive than the TBA colour reaction method.

Kinetics↗
PubMed1987

Moustachology.

Explore the source record for details and available documents.

Hair↗
PubMed1986

Ultrasonic radiation induced lipid peroxidation in liposomal membrane.

Ultrasonic radiation produced a dose dependent linear increase in lipid peroxidation (MDA formation) in the liposomal membrane. The yield of MDA was significantly inhibited by butylated hydroxytoluene (BHT), the antioxidant, sodium formate, the OH. radical scavenger, and EDTA, the metal ion chelator. Ascorbic acid at low concentration increased the ultrasonic induced MDA formation while high concentrations inhibited lipid peroxidation. A mechanism of ultrasound induced lipid peroxidation is suggested.

Ascorbic Acid↗
PubMed1986

Macrophage membrane alterations in leprosy as determined by change in sialic acid level.

The level of sialic acid removable by neuraminidase from macrophages of bacteriologically-positive lepromatous leprosy (B(+)LL) patient is extremely low, compared to macrophages from tuberculoid leprosy patients or normal individuals. On the other hand macrophages from long term treated bacteriologically-negative lepromatous leprosy (B(-)LL) patients show a much higher level of sialic acid. This higher level is drastically reduced when these macrophages from (B(-)LL) patients are allowed to phagocytose Mycobacterium leprae. This modulation could be host- and pathogen-specific. It is demonstrated that M. leprae infection brings out membrane changes in the macrophages leading to alteration in the surface molecules. Such membrane changes may cause hindrance in the ability of macrophages to participate successfully in the immune process.

Cell Membrane↗
PubMed1985

Heavy chain variable region. Multiple gene segments encode anti-4-(hydroxy-3-nitro-phenyl)acetyl idiotypic antibodies.

The hapten (4-hydroxy-3-nitrophenyl)acetyl (NP), when conjugated to carrier proteins, elicits a characteristic idiotypic response (NPb) in C57BL/6 mice. The response can be divided serologically into two distinct NPb-positive groups of antibodies. The first group consists of four crossreacting subgroups (I-IV), the second of two subgroups (V, VI). Some antibodies of subgroups I and II have been shown to express the unmutated heavy chain variable region (VH) germline gene 186.2. Antibodies of subgroups V and VI crossreact extensively with the NPa-positive antibodies of BALB/c mice. We sequenced heavy chain complementary DNA from eight hybridomas producing anti-NP antibodies. Six of these belong to subgroups V and VI, and two were NPa-positive hybridomas of BALB/c origin. All sequences were homologous to each other, and differed by approximately 80 basepairs from the 186.2 C57BL/6 germline VH gene. From our sequence and Southern blot analyses we suggest: (a) the NPb idiotypic response is the product of several VH germline genes, (b) some of these genes are very homologous to the gene coding for the BALB/c NPa idiotype, and might represent the C57BL/6 allelic forms of this gene, (c) the diversity regions of NPb and NPa-positive antibodies are diverse in length and amino acid composition, except for the first residue, which is always tyrosine, (d) all four heavy chain joining region gene segments are expressed without mutation. We discuss our data in terms of diversity in the germline VH gene repertoire, as well as diversity created by gene segment-joining events and somatic mutation.

Animals↗
PubMed1984

Diphallus.

Explore the source record for details and available documents.

Humans↗
PubMed1984

Peroxidation of the dried thin film of lipid by high-energy alpha particles from a cyclotron.

High-energy alpha particles produced a dose-dependent linear increase in different lipid peroxidation products (e.g., malondialdehyde (MDA), conjugated dienes, and hydroperoxides) in the dried thin film state. An inverse dose-rate effect was observed when the dose rate was varied by changing either the alpha-particle fluence rate or the alpha-particle energy. The antioxidants alpha-tocopherol and butylated hydroxytoluene (BHT) suppressed the alpha-particle-induced lipid peroxidation in the dried thin film state, and in this respect alpha-tocopherol was found superior to BHT. It was found that alpha-tocopherol was equally efficient in inhibiting lipid peroxidations by alpha particles and ultraviolet light.

Alpha Particles↗