Biomedical subjects
Publications and source records attributed to S A den Oudsten.
Plasma levels of malondialdehyde (MDA), indicating the sum of lipid peroxidation dependent and independent of cyclo-oxygenase activity, were measured in rheumatoid arthritis (RA) patients. MDA levels were increased in those patients most severely diseased. Higher levels of MDA correlated with more active RA.
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The authors describe 5 patients with rheumatoid arthritis; in 3 patients rupture of the synovial membrane and in 2 patients a calf cyst caused symptoms resembling a deep vein thrombosis. Contrast arthrography is of great help in differential diagnosis in conjunction with thorough anamnesis and clinical examination. The joint effusion plays a dominating role in the disease process, and treatment of the effusion is of the greatest importance for both prophylaxis and therapy of membrane rupture and calf cysts.