Purpuric nodules along a surgical scar. Metastatic malignant mesothelioma of the tunica vaginalis testis.
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Biomedical subjects
Publications and source records attributed to S A Sekula.
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The porphyrias are caused by hereditary defects in the synthesis of heme. Each porphyria is characterized by a unique enzyme defect and measurable elevations of specific heme precursors. While qualitatively normal, these precursors accumulate to cause protean signs and symptoms. Photosensitivity should raise the suspicion of a porphyria, especially in a child or a young adult. The skin, teeth and eyes may provide clues to the diagnosis in some cases.
Four proven and two suspected cases of linear IgA bullous disease with underlying malignancies have been reported in the literature. A fifth case associated with transitional cell carcinoma of the bladder is presented, and adult linear IgA bullous disease is reviewed.
Determining what constitutes true child abuse is not always easy. A child with epidermal nevus and multiple café-au-lait spots was erroneously thought to be a victim of abuse. This report details the features of epidermal nevi. We present these findings with the hope that such misdiagnoses can be avoided in the future.