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Biomedical subjects

S A Mednick

Publications and source records attributed to S A Mednick.

At least 109 records · Page 6Linked to original sources
PubMed1980

Pregnancy and delivery complications in the births of an unselected series of Finnish children with schizophrenic mothers.

Pregnancy, delivery and post partum conditions were coded from Helsinki Well Mother-Baby Clinics and Lying in hospitals for all deliveries to a birth cohort of Helsinki schizophrenic women. Greater difficulty was observed at all perinatal stages for the chronic and mild schizophrenic groups than for controls. These differences were heightened in the case of winter births.

Adult↗
PubMed1979

EEG response to sine wave modulated light in XYY, XXY, and XY men.

Ten XYY, 14 XXY, and 47 control XY men were located in a birth cohort of non-institutionalized, tall men. Their EEGs were recorded during stimulation with sine were modulated light; 2.5, 5, 10 and 20 Hz were the modulation frequencies. EEGs with and without stimulation were subjected to power spectral analysis. The frequency-specific EEG change due to visual stimulation (i.e. photic driving) was studied. The XYY subjects showed generally lower levels of driving than their XY controls. At stimulation frequencies of 10 and 20 Hz, the EEG driving in the XYY subjects were significantly smaller when measured in the same frequency bands (i.e. 10 and 20 Hz). In addition, stimulation at 10 Hz elicited a significantly smaller response at the third harmonic frequency (i.e. 30 Hz) in the XYY subjects. No consistent differences in EEG driving were detected between the XXY subjects and their XY controls, or between XXY and XYY subjects.

Adult↗
PubMed1977

EEG spectra in XYY and XXY men.

Ten XYY, 13 XXY, and 45 control XY men were located in a birth cohort of tall men (non-institutionalized), and their EEGs were subjected to computer analyses. The XYY men showed a significantly slower alpha activity and more power in the 3.3--9.6 c/sec band than their XY controls. There were no consistent EEG differences between the XXY men and their controls.

Adult↗
PubMed1977

Electroencephalograms of XYY and XXY men.

Abnormal EEGs have been reported in XYY and XXY men located in psychiatric hospitals and prisons. In general, persons resident in institutions are more likely to exhibit EEG abnormalities than "normal" population, and this bias of ascertainment has complicated the interpretation of these results. The present study was conducted in Denmark. Chromosome determinations were made on 4,140 men selected from a birth cohort of 31,438 men. Twelve XYY and 16 XXY men were detected. Appropriate XY control groups were selected from the same population. The XYY men were found to have a significantly lower average frequency of the occipital alpha activity than their controls. The XYY and XXy men showed significantly more theta activity than the controls.

Adult↗
PubMed1975

A longitudinal psychophysiological study of three-year-old Mauritian children: preliminary report.

The rationale for using the high-risk-group research design in the search for the aetiology of schizophrenia is described. A longitudinal study is being made of three-year-old Mauritian children who underwent a variety of physiological and psychological tests. Groups of these children, selected on the basis of their responses to electrodermal stimulation, are now attending nursery schools established on the island as part of this study. A control group of children do not attend nursery school. It is intended to follow-up these children over the next two decades. Mention is made of the benefits of this research to the development of para-medical and educational services in a developing country.

Child, Preschool↗
PubMed1975

Early detection and prevention of mental illness: the Mauritius project. A preliminary report.

The experimental manipulation method is in general not feasible in studies of the etiology of severe mental illness, whereas this method can be used in studies pertaining to primary prevention, because possible preventive methods would most likely be of a protective or beneficial nature. Preventive experimentation requires early detection of those individuals who will eventually become seriously mentally deviant. A study of children at a high genetic risk for schizophrenia is described. This study suggested certain autonomic nervous system variables as predictors of later serious mental breakdown. In a WHO-sponsored project in Mauritius the authors used these results for the selection of a group of children at risk for mental illness. 1,800 3-year-old Mauritian children were studied socially, psychologically, pediatrically and psychophysiologically between 1972 and 1973. 100 of these children were selected for experimental preventive intervention during their daily presence in two modern kindergartens. Members of this group were characterized by either abnormally fast autonomic recovery or autonomic nonresponding, or normal autonomic responding. A matched group of another 100 children served as a community control. The paper presents preliminary results from the screening of the 1,800 children.

Age Factors↗