Search PubMed⌕ Search

Biomedical subjects

S A Kal'ning

Publications and source records attributed to S A Kal'ning.

8 recordsLinked to original sources
PubMedDate not supplied

[The effect of M-cholinolytics on the lability of rabbit visual analyzer structures].

The influence of M-cholinolytics (amizyl, glipine, cyclozyl and 4-oxypiperidylbenzylate) in 0.01--10 mg/kg doses on EEG and photic driving in structures of the visual analyser was studied in experiments on twenty intact rabbits with chronically implanted electrodes in the optic chiasm, the optic tract, the lateral geniculate body and the visual cortex. All M-cholinolitics in the doses studied produced synchronization of the EEG. Photic stimulation against the background of small doses of M-cholinolytics (0.01--0.5 mg/kg) did not lead to any disturbances of photic driving. With increased doses of cholinolitics up to 1--5 mg/kg only low frequencies (1--5 imp/sec) produced driving in the lateral geniculate body and the visual cortex, while in the optic tract the driving remained at the initial level. Administration of drugs in a 10 mg/kg dose resulted in complete depression of the driving response in the lateral geniculate body and visual cortex, while in the optic tract the driving was retained.

Animals↗
PubMedDate not supplied

[Effect of cholinolytics on the functional lability of the visual analyzer in cats].

The effect of aminoethers of derivates of glycolic acid (glipine and amizil) in doses of 0.1--5 mg/kg and of derivates of acetic acid (diphacyl and thropacin) in doses of 10--40 mg/kg on bioelectrical activity of the retina was studied in experiments on 10 intact cats. To control the effect of cholinolytics, electrodes were chronically implanted in the visual cortex and EEG ws recorded. It was noted that the frequency of white, yellow, green and blue photic stimuli is reproduced on ERG within the range from 1 to 23 c/s both before the administration of cholinolytics and during their action in all of the used doses. Flash rhythm reproduction was not disturbed (in spite of an increase in the waves' amplitudes in the retinal background bioelectrical activity) following administration of cholinolytic substances. All cholinolytics in all of the studied doses caused in the EEG of the visual cortex an increase in waves' amplitude, i. e. a synchronization.

Animals↗