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Biomedical subjects

S A Estes

Publications and source records attributed to S A Estes.

At least 37 records · Page 2Linked to original sources
PubMed1983

Erysipeloid.

Erysipelothrix infections have been a well-known clinical entity for over a century. Only a few cases have been studied histologically, and the agent has rarely been cultured from infected patients. We present here a case of erysipeloid of Rosenbach, in which histologic study and electron microscopy document the presence of microorganisms. We also present a complete review of the clinical and pathologic features of Erysipelothrix infections and their treatment. Our observations suggest that Erysipelothrix rhusiopathiae is capable of producing L forms that may revert to a bacterial form and produce sepsis at a later time.

Erysipeloid↗
PubMed1983

Experimental canine scabies in humans.

Adult female Sarcoptes scabiei var. canis mites were applied to human skin for 96 hours in an experimental chamber. Clinical lesions produced during this period were studied histologically. The organisms burrowed, defecated, and laid up to nine eggs that developed normally. Two eggs hatched after removal from the host. A life cycle was not completed during this short experiment, but these results suggest canine scabies are capable of such activities on human skin.

Animals↗
PubMed1983

Relapsing polychondritis. A case report and literature review.

Relapsing polychondritis is a systemic disorder characterized by recurrent inflammation and degeneration of cartilaginous tissue. The eyes, ears, nose, larynx, trachea, and articular areas are commonly involved. While ocular involvement, hearing, and vestibular dysfunction are frequently present, aortic valve and root disease as well as vasculitis also may occur. While the cause remains unknown, an autoimmune pathogenesis appears likely. Thus, dapsone and/or systemic corticosteroids remain the predominant effective therapies. Another case of relapsing polychondritis with an associated vasculitis syndrome is presented as well as a review of the current literature.

Arthritis, Rheumatoid↗
PubMed1981

Delayed pressure urticaria: an investigation of some parameters of lesion induction.

Two patients with delayed pressure urticaria were studied to define some of the physical parameters related to experimental lesion induction using a pressure-testing device. Graded pressures from 48 to 234 gm/mm2 were applied for 1 to 180 seconds on several anatomic areas. Experimentally induced lesions were symptomatically, clinically, and histologically identical to spontaneous wheals and reached a maximum size 9 hours after the stimulus. The threshold response found was related to the amount of pressure, the duration it was applied, and the anatomic area tested. Sites that previously reacted to pressure were refractory to additional stimuli for at least 24 to 48 hours. The mediator for delayed pressure urticaria remains unknown, and some patients do not respond to oral corticosteroids.

Adult↗
PubMed1981

Symptomatic dermographism.

Urticaria is caused by physical factors in almost 12 percent of cases. These factors include pressure. Dermographism is the appearance of whealing and erythema within minutes where skin has been exposed to pressure or mechanical irritation. Symptomatic dermographism is present when "normal" pressures, such as those encountered in the activities of daily living, cause urticaria. Individuals with symptomatic dermographism can be shown to have a lower pressure threshold for the production of dermographism than normal individuals. A case of symptomatic dermographism is presented, and the differential diagnosis is discussed.

Adult↗
PubMed1981

Infestivity of Psoroptes cuniculi in rabbits.

Starving Psoroptes cuniculi were found to survive off the host for 4 to 21 days at relative humidities between 20% and 99% and temperatures between 5 and 30 C. Within these extremes, survival was greatest at low temperature and high relative humidity (RH). Mites were infestive for at least 50% of their survival times and may have infested new hosts in contaminated facilities. A temperature of 40 C and 20% RH maintained for 24 hours caused 100% mortality in test mites. Other selected combinations of temperature above 40 C and RH less than or equal to 75% also caused 100% mortality in 2 days or less. These conditions could be used to control these mites in vacated contaminated premises.

Animals↗
PubMed1980

Subungual epidermal cyst.

A patient developed a painful subungual lesion which was an epidermal cyst on biopsy. The incidence and pathogenesis of subungual epidermal cysts are reviewed. This usually asymptomatic tumor should be considered in the differential diagnosis of subungual lesions.

Adult↗
PubMed1980

Primary cutaneous aspergillosis.

A 6-year-old boy with acute monocytic leukemia and therapy-induced leukopenia developed multiple necrotizing skin lesions where an intravenous administration unit had been secured to his arm and hand. Biopsy and cultures demonstrated Aspergillus flavus as the etiologic agent without evidence of systemic dissemination. Resolution of the infection occurred following systemic amphotericin B therapy and a granulocyte transfusion.

Amphotericin B↗
PubMed1980

Behavior therapy techniques in treatment of exfoliative dermatitis.

We report here a case study in which behavior therapy techniques were used to treat the persistent and severe scratching of a patient with long-standing exfoliative dermatitis. A multiple-baseline clinical design across different body areas was used to evaluate the behavioral treatment program. This program consisted of (1) training the patient to monitor his scratching behavior and to use an incompatible response and distraction procedure contingent on the occurrence of scratching, and (2) differential attention by the therapist, so that the therapist's attention was contingent on intervals of nonscratching, and the therapist ignored the patient when he did scratch. The results indicated that the program was effective in almost completely eliminating scratching when a variety of therapists were and were not present. This suggests that the procedures used might easily be taught to the nursing staff.

Adult↗
PubMed1977

Primary cutaneous phaeohyphomycosis caused by Drechslera spicifera.

A primary cutaneous lesion in a 5-year-old boy who had recently received chemotherapy for acute lymphocytic leukemia was found to be caused by a dematiaceous fungus, Drechslera spicifera. The lesion was an erythematous macule that rapidly developed necrotic ulcerations. The fungus, which is commonly found in soil and as a plant pathogen, was isolated from cultures of the lesion and from an excisional biopsy specimen. Hyphae and swollen hyphal cells resembling chlamydospores were observed in the biopsy specimen. Septate pigmented hyphae were found in the tissue, which is consistent with phaeohyphomycosis. Resolution of the infection occurred following excisional biopsy and systemic amphotericin B therapy. There was a concomitant recovery from neutropenia.

Child, Preschool↗