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Biomedical subjects

Russell L Woods

Publications and source records attributed to Russell L Woods.

5 recordsLinked to original sources

Contour integration in peripheral vision reduces gradually with eccentricity.

Hess and Dakin reported that normally-sighted subjects using peripheral vision (beyond 10 degrees ) were unable to detect paths of alternating-phase Gabors embedded within randomly positioned Gabors, but could detect same-phase paths. This result led them to propose a "fundamental difference" between central and peripheral visual processing. While we were able to replicate many of their results, our normally-sighted observers could detect alternating-phase paths beyond 10 degrees. We found that path detection decreased monotonically as a function of eccentricity (0 degrees -30 degrees ) for both alternating-phase and same-phase stimuli. As with most visual functions the more difficult path detection condition (alternating-phase) declined slightly faster. The results for the normally-sighted observers could not be explained by poor fixation. Three people with substantial central vision loss (i.e. they can only use peripheral vision) could see both same- and alternating-phase stimuli with eccentric viewing of 13 degrees -17 degrees. Therefore central and peripheral vision appear to use similar visual mechanisms to perform the task, there being no fundamental difference.

Adult↗

Comparison of monochromatic ocular aberrations measured with an objective cross-cylinder aberroscope and a Shack-Hartmann aberrometer.

Repeated measures of wavefront aberrations were taken along the line-of-sight of seven eyes using two instruments: an objective, cross-cylinder aberroscope (OA) and a Shack-Hartmann (SH) aberrometer. Both instruments were implemented on the same optical table to facilitate interleaved measurements on the same eyes under similar experimental conditions. Variability of repeated measures of individual coefficients tended to be much greater for OA data than for SH data. Although Zernike coefficients obtained from a single measurement were generally larger when measured with the OA than with the SH, the averages across five trials were often smaller for the OA. The Zernike coefficients obtained from the two instruments were not significantly correlated. Radial modulation-transfer functions and point-spread functions derived from the two sets of measurements were similar for some subjects, but not all. When average Zernike coefficients were used to determine optical quality, the OA indicated superior optics in some eyes, but the reverse trend was true if Zernike coefficients from individual trials were used. Possible reasons for discrepancies between the OA and SH measurements include difference in sampling density, quality of data images, alignment errors, and temporal fluctuations. Multivariate statistical analysis indicated that the SH aberrometer discriminated between subjects much better than did the objective aberroscope.

Diagnostic Techniques, Ophthalmological↗

Lateral interactions: size does matter.

Usually a high-contrast, co-local mask increases contrast threshold (inhibition). Interestingly, a laterally displaced mask (flanker) can facilitate contrast detection (Vision Research 33 (1993) 993; 34 (1994) 73). When spatial scaling of these flanker effects was implied, stimulus bandwidth was confounded with spatial frequency (lambda(-1)). Under conditions where at lower spatial frequencies, the size (standard deviation, sigma) of the Gabor patch was smaller (sigma<lambda) than higher spatial frequencies (sigma=lambda), the effect appeared scale invariant. We replicated the original results for all conditions. However, when Gabor size was fixed (sigma=lambda), facilitation changed with spatial frequency (range 2--13 cycles/deg). When Gabor size was varied (sigma=0.5-2 lambda), usually the combination of larger patch sizes and lower spatial frequencies caused inhibition. We were unable to find any conditions that demonstrated spatial scaling. The size, both lambda and sigma, of both stimulus and flankers, influenced contrast threshold. Also, facilitation reduced as contrast of the flankers was reduced to detection threshold. Some facilitation was apparent with sub-threshold flankers. These results need to be reconciled with current models of lateral interactions.

Adult↗

Vision and mobility performance of subjects with age-related macular degeneration.

PURPOSE: To investigate the effects of age-related macular degeneration (ARMD) on mobility performance and to identify the vision determinants of mobility in subjects with ARMD. METHODS: Walking speed and the number of obstacle contacts made on a 79-m indoor mobility course were measured in 21 subjects with ARMD and 11 age-matched subjects with normal vision. The mobility measures were transformed to percentage preferred walking speed and contacts score. The vision functions assessed included binocular visual acuity, contrast sensitivity, and visual field. RESULTS: In this study, subjects with ARMD did not walk significantly slower or make significantly more obstacle contacts on the mobility course than the normally sighted subjects of similar age. Between 29% and 35% of the variance in the ARMD mobility performance was accounted for by visual field and contrast sensitivity measures. The most significant predictor of mobility performance scored as percentage preferred walking speed was the size of a binocular central scotoma. CONCLUSION: As the size of a binocular central scotoma increases, mobility performance decreases.

Aged↗

Stereoacuity at distance and near.

PURPOSE: Because previous studies have reported conflicting evidence, we examined a possible difference in stereoacuity between distance and near, in particular using a random-dot display. We compared distance and near stereoacuities using identical presentation formats at the two distances. METHODS: Twelve young adults with low, stable refractive errors and apparently normal binocular vision participated. Stereoacuity was determined with a Mentor B-VAT II using Random Dot E (BVRDE) and Contour Circles (BVC) stereograms presented on a standard monitor (25 x 19.3 cm) at 518 cm (distance-habitual) and a small monitor (2.0 x 1.4 cm) at 40 cm (near-habitual). To examine whether accommodation-convergence influenced stereoacuity, testing at 40 cm was repeated with the addition of +2.50 DS lenses and base-in prisms (near-compensated) that created the same accommodation and convergence demands as for distance-habitual viewing. RESULTS: The two stereotests produced similar findings. Stereoacuity was not significantly different for distance-habitual and near-habitual viewing of the BVRDE (p = 0.43) and BVC (p = 0.79) stereotests. Near-compensated stereoacuity was worse than near-habitual (BVRDE, p = 0.005; BVC, p = 0.004) and distance-habitual (BVRDE, p = 0.05; BVC, p = 0.003) for both stereotests. Because near stereoacuity with yoked prisms (control condition) was the same as without prism (near-habitual), prism-induced optical distortions cannot account for the difference. CONCLUSIONS: Stereoacuity was not different at distance and near under normal viewing conditions. The conflict between subject knowledge of target proximity and the optically-induced relaxation of accommodation and convergence, or an inaccurate accommodative-convergence response, might have caused poor near-compensated stereoacuity.

Accommodation, Ocular↗