Search PubMed⌕ Search

Biomedical subjects

Richard Fielding

Publications and source records attributed to Richard Fielding.

At least 19 recordsLinked to original sources

Change in quality of life in Chinese women with breast cancer: changes in psychological distress as a predictor.

INTRODUCTION: The effect of fluctuating psychological distress on quality of life (QoL) scores is not well delineated. We examined how changes in psychological distress affected change in QoL over time in 259 Chinese women recovering from breast cancer (BC). PATIENTS AND METHODS: Women were interviewed during their first postoperative outpatient visit for chemotherapy (Baseline), at 3 months (FU1), and at 6 months after Baseline (FU2). Respondents completed the Chinese version of the FACT-G version-3 scale [FACT-G (Ch)]. Psychological distress was assessed using three categorical measures of depression, mood, and boredom. Linear mixed effects (LME) models examined whether changes in psychological distress predicted subsequent changes in QoL. RESULTS: Respondents' mood improved significantly over time from baseline to FU2 (Baseline/FU2: standardized beta = -0.266, p < 0.005; FU1/FU2: standardized beta = -0.243, p < 0.005). Changes in depression scores consistently predicted subsequent changes in overall (standardized beta = 4.96; 95% CI, 3.749, 6.171, p < 0.001), physical (standardized beta = 1.752; 95% CI, 1.209, 2.294, p < 0.001), and functional (standardized beta = 0.872; 95% CI, 0.308, 1.436, p < 0.001) QoL scores. CONCLUSIONS: The magnitude of change in psychological distress significantly impacted physical and functional, but not social QoL in Chinese BC patients. These data highlight the need to address psychological and physical distress as part of the drive to improve physical and functional QoL for women with BC.

Adult↗

Is self-efficacy a predictor of short-term post-surgical adjustment among Chinese women with breast cancer?

BACKGROUND: High self-efficacy (SE) is regarded as beneficial for cancer patients in facilitating adaptation and therefore desirable. However, this may not always be the case. DESIGN: A longitudinal cohort study of women receiving breast cancer surgery. Path analysis examined impact of high and low baseline SE scores on outcome. Post hoc analysis stratified outcome expectations by SE. METHODS: 405/529 eligible Chinese women aged 28-79 years receiving breast cancer surgery in six regional Hong Kong hospitals were interviewed within 1 week of surgery. After assessing SE, incongruence between expectancy and outcome of surgery (E-OI), and psychological morbidity, 91% of women were followed for 1 month when psychological and social morbidity were assessed (follow-up). RESULTS: After adjustment for demographic and histopathological factors, psychological morbidity was predicted by E-OI. Women with high E-OI had more impairment of sexuality and self-image. Women with high SE had better self-image and relationships with friends, but tended to underestimate the negative consequences of surgery on appearance. This increased E-OI and thereby psychological morbidity. CONCLUSIONS: High post-surgical SE benefits early social adaptation, but also leads to under-estimating the negative impacts of surgery, impairing psychological adjustment. High SE can thereby contribute indirectly and significantly to increased psychological morbidity.

Adaptation, Psychological↗

Treatment decision difficulties and post-operative distress predict persistence of psychological morbidity in Chinese women following breast cancer surgery.

BACKGROUND: The patterns and determinants of longer-term psychological morbidity in women following breast cancer surgery have not been described for Chinese populations. METHODS: Chinese women were assessed at 3-days, 4-months and 8-months following breast surgery, on treatment decision-making difficulty (TDMD), satisfaction with treatment outcome (E-OI), self efficacy (GSeS), optimism (C-LOT-R), consultation satisfaction (C-MISS-R), physical symptom distress (PSD) and psychological morbidity (CHQ-12) and compared using polynomial logistic models. RESULTS: Of 303/405 women providing complete data, 33% received chemotherapy and 26% radiotherapy. GSeS, CLOTR and TDMD scores were moderate. Though the proportion of women meeting psychological morbidity case-criteria declined from 78% (95% Confidence Interval 73-83%) at Baseline to 64% (59-69%) at 8-months, almost 50% (44-54%) of women remained distressed over the 8-month period. After adjustment for demographic and clinical factors, severity of psychological morbidity at 4-months was predicted by PSD, disappointment and higher Baseline CHQ12, and among moderate/severe cases only, greater TDMD and pessimistic outlook. At 8-months, CHQ12 scores were predicted by PSD, Baseline CHQ-12, and difficulties with TDM. CONCLUSION: TDM difficulties, early post-surgical psychological and physical symptom distress indicate risk for prolonged distress in Chinese women following breast cancer surgery.

Adaptation, Psychological↗

Age- versus time-comparative self-rated health in Hong Kong Chinese older adults.

OBJECTIVES: The main objectives were to examine the relation between age-comparative (self vs others of same age) self-rated health (SRH) and time-comparative (self this year vs last year) SRH, and to evaluate which was more strongly associated with specific physical health problems. METHODS: Cross-sectional data on two SRH measures and various physical health problems from 18749 male and 37413 female clients aged 65 or over from 18 Elderly Health Centres in Hong Kong were analysed using logistic regression with adjustment for potential confounders. RESULTS: Men were more likely to report 'better' and less likely to report 'worse' SRH than women. 'Normal' was the most common option but the proportions choosing this decreased with age on both SRH measures. There was a fairly weak but statistically significant correlation between these two measures, with Kappa coefficients of 0.125 and 0.167 for men and women, respectively. For both men and women, there were significantly positive linear trends between age-comparative SRH options from 'better' to 'worse' and physical health problems, such as respiratory diseases, musculoskeletal diseases, any active chronic diseases, functional disability, depressive symptoms, taking medication regularly, and admission to hospital last year. However, for time-comparative SRH, those who rated 'normal' had the smallest odds ratios in all of the physical health problems above than those who rated 'better' or 'worse'. CONCLUSIONS: The two SRH measures correlated with each other weakly but significantly. Age-comparative SRH was linearly, and time-comparative SRH was curvilinearly associated with physical health problems.

Age Factors↗

Risk-behavior reporting by blood donors with an automated telephone system.

BACKGROUND: Donor risk-behavior assessment is important for blood safety. Few evaluations of automated telephone systems for eliciting risk exposure among voluntary blood donors have been reported. STUDY DESIGN AND METHODS: A modified risk-behavior questionnaire was presented after donation via an automated telephone polling system to 805 of 15,092 Hong Kong Chinese voluntary blood donors. Risk-behavior rates were compared to those of all other donors (14,287) simultaneously completing the questionnaire in a pencil-and-paper format. RESULTS: The telephone group included proportionally more women (46.3% vs. 44.9%), previous donors (93.3% vs. 83.6%), and sexually inactive donors (66.5% vs. 71.2%) with lower educational achievement (60.7% vs. 54.5%). The telephone group demonstrated fewer missing data (mean 1.3%, range 0.4%-3.1% vs. mean 9.8%, range 8.0%-14.2%) and more complete demographic detailing, probably accounting for the demographic differences. The telephone group reported higher prevalence rates of needle or syringe sharing (1.5% vs. 0.3%), homosexual and/or bisexual intercourse (4.1% vs. 1.3%), knowing or suspecting that partner had intercourse with another during past year (12.4% vs. 8.5%), and future intention to use blood donation as a means to test for human immunodeficiency virus (HIV; 19.1% vs. 13.7%). There was no difference in knowledge of the HIV window period or proportions visiting or using condoms with commercial sex workers between telephone and pencil-and-paper groups. CONCLUSION: This survey with automated telephone screening of potential blood donors revealed increased reporting of risk exposure relative to commonly used paper-and-pencil methods. This raises questions of possible underreporting of risk among blood donors screened by paper questionnaire and perhaps face-to-face interview.

Adolescent↗

Longitudinal assessment of community psychobehavioral responses during and after the 2003 outbreak of severe acute respiratory syndrome in Hong Kong.

BACKGROUND: In previous literature, the stability and temporal evolution of psychobehavioral responses to an outbreak remained undefined, because of the exclusively cross-sectional nature of such study designs. METHODS: Using random-digit dialing, we sampled 4481 Hong Kong residents in 6 population-based surveys that were conducted at different times during and after the 2003 outbreak of severe acute respiratory syndrome (SARS). RESULTS: Respondents' State-Trait Anxiety Inventory score (range, 10-40) showed a decreasing temporal trend, from a high mean value of 24.8 during the peak of the Amoy Gardens outbreak to a postepidemic mean baseline value of 14.5. Those who perceived a higher likelihood of contracting or dying of SARS had significantly higher anxiety scores. Female respondents, individuals aged 30-49 years, and individuals with only a primary education or less were predisposed to greater anxiety. There was a positive dose-response gradient between anxiety level and uptake of personal protective measures. Males respondents, individuals at the extremes of age, and individuals with lower educational levels were less likely to engage in self-protective behavior. The presence of symptoms was the only consistent predictor for greater use of health services. There was remarkable stability in the magnitude and the direction of associations between predictors and outcomes over time. CONCLUSIONS: Our findings can assist in modifying public service announcements in the future, which should be tailored to psychobehavioral surveillance intelligence to achieve the desired behavioral outcomes. Future research should explore the use of more-sophisticated techniques, including structural equation modeling and game-theoretical frameworks, to analyze population psychology and behavior, and it should integrate such findings with transmission dynamics modeling.

Adult↗

Short-term, medium-term, long-term, and lifetime risks of developing and dying of breast carcinoma in a Westernized Chinese population: Evidence from Hong Kong between 1976 and 2000.

BACKGROUND: Estimates of lifetime and shorter-term risks of developing and dying of breast carcinoma are useful translational statistics for risk communication; however, these statistics are unknown for Chinese women, who account for one-fifth of the world's female population. In the current study, the authors examined age-specific 5-year, 10-year, 20-year, and lifetime risks of breast carcinoma incidence and disease-related mortality among Hong Kong women. METHODS: Multiple-decrement life tables were constructed by applying age-specific incidence and mortality rates obtained from cross-sectional data to a hypothetic birth cohort. Incidence, mortality, and population data from 1976 through 2000 were used. RESULTS: For Hong Kong women in the period 1996-2000, the overall lifetime risk of developing invasive breast carcinoma was 5.7% (1 in 17), compared with 10.6% (1 in 9) for U.S. Asian/Pacific Islander women and 14.5% (1 in 7) for U.S. white women. The lifetime breast carcinoma-related mortality risk for Hong Kong women in that same period was 1.7% (1 in 58). For women age 50 years, the 5-, 10-, and 20-year risks of developing breast carcinoma were 0.6% (1 in 172), 1.1% (1 in 87), and 2.1% (1 in 47), respectively. The absolute lifetime probability of developing breast carcinoma increased from 3.81% (1 in 26) during the period 1976-1980 to 5.73% (1 in 17) during the period 1996-2000; 44.5% of this change can be attributed to the increased longevity of women in the latter time period, and the remaining 55.5% can be ascribed to a secular rise in breast carcinoma incidence. CONCLUSIONS: As China becomes more Westernized, the authors expect that the risks of developing and dying of breast carcinoma for Chinese women will become more similar to the corresponding risks for Western women. The current data from Hong Kong, the most Westernized Chinese community, appear to support this conclusion.

Adult↗

Predicting psychological morbidity in Chinese women after surgery for breast carcinoma.

BACKGROUND: Between 30% and 70% of western women experience psychological morbidity after undergoing surgery for breast carcinoma; however, the rates and risk factors among Chinese women are unknown. Identifying at-risk women enables preventive intervention. METHODS: Among 430 Chinese women who were approached within 1 week after undergoing surgery for early-stage breast carcinoma (baseline), 405 women (94%) completed measures of self-efficacy and psychological morbidity (the Chinese Health Questionnaire 12-item instrument [CHQ12]) and completed retrospective measures of treatment decision-making (TDM) difficulties, satisfaction with TDM involvement, and satisfaction with consultation and treatment outcome expectations. One-month postsurgery follow-up (follow-up), CHQ12 scores for 367 of 405 women (91%) were adjusted for concurrent physical symptom distress and trait optimism (the revised Chinese Life Orientation Test) and baseline predictors using stepwise multivariate regression. RESULTS: At baseline 28% of women evidenced mild psychological morbidity, and 42% of women evidenced moderate-to-severe psychological morbidity: At follow-up, the respective rates were 32% and 36%. Preferred TDM involvement was associated with lower psychological morbidity (F = 6.702; P < 0.001). Baseline CHQ12 scores were predicted by outcome expectancies and TDM difficulties (adjusted regression coefficient [R(2)] = 0.192). Baseline CHQ12 scores and follow-up chemotherapy, in turn, predicted physical symptom distress at follow-up. After adjustment, high physical symptom distress, baseline psychological morbidity, low optimism, and no chemotherapy independently predicted follow-up CHQ12 scores (adjusted R(2) = 0.585). CONCLUSIONS: Psychological morbidity was linked to women's TDM difficulties, their inability to anticipate treatment effects accurately, and physical symptom distress, possibly exacerbated by symptom misattribution. Optimizing TDM support and helping women accurately determine outcomes in terms of symptom experience and meaning and physical appearance may help to reduce psychological morbidity. Women who have TDM difficulties should be considered to be at high risk for psychological distress.

Adult↗

Gambling with your life: the process of breast cancer treatment decision making in Chinese women.

Treatment decision making (TDM) studies have primarily focused on assessing TDM quality and predominantly presume rational analytic processes as the gold standard. In a grounded theory study of 22 Hong Kong Chinese women following breast surgery who completed an in-depth interview exploring the process of TDM in breast cancer (BC), narrative data showed that discovery of a breast abnormality and emotional responses to BC diagnosis influence the TDM process. Lack of guidance from surgeons impaired TDM. Decisions were, for the most part, made using intuitive, pragmatic and emotionally driven criteria in the absence of complete information. The experience of TDM, which was likened to gambling, did not end once the decision was made but unfolded while waiting for surgery and the post-operative report. In this waiting period, women were emotionally overwhelmed by fear of death and the uncertainty of the surgical outcome, and equivocated over whether they had made the 'right' choice. This suggests that Chinese women feel they are gambling with their lives during TDM. These women are particularly emotionally vulnerable whilst waiting for their surgery and the post-surgical clinical pathology results. Providing emotional support is particularly important at this time when these women are overwhelmed by uncertainty.

Adult↗

Surgeon's recommendation, perceived operative efficacy and age dictate treatment choice by Chinese women facing breast cancer surgery.

PURPOSE: to identify factors influencing Chinese women's choices between breast-conserving therapy (BCT), mastectomy (MRM) or MRM followed by breast reconstruction (MRM+R). METHODS: of 405/443 Hong Kong Chinese women receiving surgery for early breast cancer who were interviewed one week post-surgery about their pre-surgical consultation, available treatment alternatives, whether their surgeons had indicated a surgical preference, perceived efficacy of the surgical options and considerations influencing their treatment decisions (TDM), 198 (49%) reported they were offered a choice of surgery. RESULTS: among women offered a choice of surgery, BCT was chosen by 34/43 (79%) of women whose surgeons recommended BCT but by only 34/96 (37%) of women whose surgeons expressed no treatment recommendation. Multivariate adjustment showed women choosing MRM were influenced more by avoiding both cancer recurrence (p = 0.003) and further treatment (p = 0.009) when choosing surgical option than women choosing BCT. In contrast, women choosing MRM+R and BCT, placed more emphasis on appearance (p < 0.001) and body image (p < 0.001) concerns as influencing treatment choice than did women who chose MRM. CONCLUSION: survival concerns rather than physical appearance, age and lack of recommendation push Chinese women to choose MRM as BCT is, incorrectly often seen as less efficacious. Recommending BCT increases BCT choice.

Adult↗

Avian influenza risk perception, Hong Kong.

A telephone survey of 986 Hong Kong households determined exposure and risk perception of avian influenza from live chicken sales. Householders bought 38,370,000 live chickens; 11% touched them when buying, generating 4,220,000 exposures annually; 36% (95% confidence interval [CI] 33%-39%) perceived this as risky, 9% (7%-11%) estimated >50% likelihood of resultant sickness, whereas 46% (43%-49%) said friends worried about such sickness. Recent China travel (adjusted odds ratio 0.35; CI 0.13-0.91), traditional beliefs (1.20, 1.06-1.13), willingness to change (0.29, 0.11-0.81) and believing cooking protects against avian influenza (8.66, 1.61-46.68) predicted buying. Birth in China (2.79, 1.43-5.44) or overseas (4.23, 1.43-12.53) and unemployment (3.87, 1.24-12.07) predicted touching. Age, avian influenza contagion worries, husbandry threat, avian influenza threat, and avian influenza anxiety predicted perceived sickness risk. High population exposures to live chickens and low perceived risk are potentially important health threats in avian influenza.

Adolescent↗

Sexually transmitted infections in travelers: implications for prevention and control.

Sexually transmissible diseases (STDs), the most common notifiable infectious conditions, remain major threats to reproductive and public health worldwide. Travelers are particularly vulnerable to STDs, because of voluntary or involuntary sexual behavior while abroad, and are significant vectors who introduce new pathogens and resistant strains to unaffected parts of the world. This article outlines some key issues that travel medicine specialists and other clinicians should revisit when providing services to travelers. We discuss obstacles to promoting sexual health, including the diversity of the target group, unanticipated opportunities for sexual risk, ambivalent cooperation by the travel and tourism industries, poorly developed travel health sectors, illegal migration and sex tourism, and lack of research about the association between travel and STDs. We also outlined some programmatic aspects of public health that should be identified and addressed for the promotion of sexual health among travelers.

Humans↗

Measuring social impacts of breast carcinoma treatment in Chinese women.

BACKGROUND: There is no existing instrument that is suitable for measuring the social impact of breast carcinoma (BC) and its treatment among women of Southern Chinese descent. In the current study, the authors assessed the validity of the Chinese Social Adjustment Scale, which was designed to address the need for such an instrument. METHODS: Five dimensions of social concern were identified in a previous study of Cantonese-speaking Chinese women with BC; these dimensions were family and other relationships, intimacy, private self-image, and public self-image. The authors designed 40 items to address perceptions of change in these areas. These items were administered to a group of 226 women who had received treatment for BC, and factor analysis subsequently was performed to determine construct characteristics. The resulting draft instrument then was administered, along with other measures for the assessment of basic psychometric properties, to a second group of 367 women who recently had undergone surgery for BC. RESULTS: Factor analysis optimally identified 5 factors (corresponding to 33 items): 1) Relationships with Family (10 items, accounting for 22% of variance); 2) Self-Image (7 items, accounting for 15% of variance); 3) Relationships with Friends (7 items, accounting for 8% of variance); 4) Social Enjoyment (4 items, accounting for 6% of variance); and 5) Attractiveness and Sexuality (5 items, accounting for 5% of variance). Subscales were reliable (alpha = 0.63-0.93) and exhibited convergent validity in positive correlations with related measures and divergent validity in appropriate inverse or nonsignificant correlations with other measures. Criterion validity was good, and sensitivity was acceptable. Patterns of change on the scales were consistent with reports in the literature. Self-administration resulted in improved sensitivity. CONCLUSIONS: The 33-item Chinese Social Adjustment Scale validly, reliably, and sensitively measures the social impact of BC on Cantonese-speaking Hong Kong Chinese women. Further development of the scale to increase its sensitivity is underway.

Adult↗

Evaluation of a handheld clinical decision support tool for evidence-based learning and practice in medical undergraduates.

INTRODUCTION: Handheld computers (PDAs) uploaded with clinical decision support software (CDSS) have the potential to facilitate the adoption of evidence-based medicine (EBM) at the point-of-care among undergraduate medical students. Further evaluation of the usefulness and acceptability of these tools is required. METHODS: All 169 Year 4 undergraduate medical students at the University of Hong Kong completed a post-randomised controlled trial survey. Primary outcome measures were CDSS/PDA usefulness, satisfaction, functionality and utilisation. Focus groups were also conducted to derive complementary qualitative data on the students' attitudes towards using such new technology. RESULTS: Overall, the students found the CDSS/PDA useful (mean score = 3.90 out of 6, 95% confidence interval (CI) = 3.78, 4.03). They were less satisfied with the functional features of the CDSS (mean score = 3.45, 95% CI = 3.32, 3.59) and the PDA (mean score = 3.51 95% CI = 3.40, 3.62). Utilisation was low, with the average frequency of use less than once per week. Although students reported a need for information in patient care at least once daily, they infrequently used the CDSS in a clinical setting (20.4 +/- 10.4% of the time), with an average information retrieval success rate of 37.6 +/- 22.1% requiring 63.7 +/- 86.1 seconds. Multivariable regression shows that higher perceived CDSS/PDA usefulness was associated with more supportive faculty attitudes, greater knowledge of EBM, better computer literacy skills and increased use in a clinical setting. Greater satisfaction with the CDSS/PDA was associated with increased use in a clinical setting and higher successful search rates. Qualitative results were consistent with these quantitative findings and yielded additional information on students' underlying feelings that may explain the observations. CONCLUSIONS: While PDAs uploaded with the CDSS are able to provide students with better access to high quality information, improvements in faculty attitudes, students' knowledge of EBM and computer literacy skills, and having the CDSS specially designed for undergraduate use are essential to increasing student adoption of such point-of-care tools.

Attitude of Health Personnel↗

Determinants of HIV antibody testing among selected groups of Chinese residents in Hong Kong.

HIV testing is promoted to the public as a tool for HIV prevention in many countries. However, the patterns and determinants of HIV antibody testing among the Chinese people are unknown. To describe the prevalence and determinants of HIV antibody testing amongst the Hong Kong Chinese a cross-sectional anonymous survey was carried out among 1,027 subjects from different population groups (airport travellers, business sector workers, service sector workers, university staff, and STD clinic attendees). Subjects were categorized into either 'STD population' (respondents from STD clinics) versus 'all others' (respondents from other settings) groups. Forty-five percent of the respondents reported ever having had a test for HIV antibody. 'STD population' group members were almost three times more likely to have had an HIV test than were 'all others' group members (77% vs 20%). After adjustments, 'STD population' group members who reported having tested for HIV were more often aged 45 years or older, alcohol drinkers, with high self-efficacy scores, and inconsistent condom users; members in the 'all others' group, more often had had sex with strangers, drank alcohol, and favoured having multiple sex partners. Awareness among the public about the risk behaviours for HIV should be enhanced and efforts should be made to reduce high-risk behaviours among those tested by emphasizing the importance of maintaining safer sex behaviour and having follow-up tests during post-test counselling.

Adult↗

Subjective health and fibrinogen in a healthy Chinese cohort.

OBJECTIVES: This study explores standard cardiovascular (CVD) risk factors in a healthy population sample, with low CVD prevalence and presumed higher social connectedness as potential mechanisms linking subjective health (SH) and physical health. METHOD: A population-based, telephone-sampled, cross-sectional study recruited a healthy subset of 2280 Chinese adults who subsequently underwent a free medical examination. Serum total cholesterol, low-density lipoproteins (LDL), high-density lipoproteins (HDL), triglycerides, fibrinogen, fasting glucose, 2-hour post-load glucose, blood pressure and adiposity were compared between respondents reporting good SH and those reporting poor SH over the past 3 months, on a 4-point, single-item measure. RESULTS: After adjustment for age, gender, education, exercise, marital and smoking status, only serum fibrinogen significantly differentiated the two groups. Respondents reporting Very poor or Poor SH had a significantly greater likelihood of raised mean fibrinogen levels compared with those reporting Good or Very good SH (Adjusted Odds Ratio 1.37, 95% CL 1.002-1.84, p < .05). CONCLUSIONS: There is a small but robust association between SH and fibrinogen in this low CVD prevalent population unexplained by known pre-existing disease.

Adult↗