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Biomedical subjects

Richard F Horan

Publications and source records attributed to Richard F Horan.

4 recordsLinked to original sources

Vancomycin-induced linear IgA bullous dermatosis: morphology is a key to diagnosis.

Vancomycin-induced linear IgA bullous dermatosis (LABD) previously has been described; however, past reports have suggested that the clinical presentation is nonspecific. We present a case of vancomycin-induced LABD with a suggestive clinical presentation; specifically, groups of annularly arranged vesicles. We propose that this clinical presentation strongly suggests drug-induced LABD and should raise a clinician's suspicion of vancomycin as the offending agent. This awareness may guide the antibiotic management of the patient while the clinician awaits histopathologic correlation.

Biopsy, Needle↗

Exercise-induced Anaphylaxis.

Exercise-induced anaphylaxis has been recognized with increasing frequency since its original description in 1980. Recent studies suggest food-induced reactions may occur frequently in this syndrome, which is a mast cell-dependent phenomenon. In this article, the clinical manifestations of exercise-induced anaphylaxis are reviewed, and food-related factors contributing to the disorder are considered.

Anaphylaxis↗

Hot tub-related Mycobacterium avium intracellulare pneumonitis.

Atypical Mycobacteria have been widely known to cause opportunistic infections in patients with AIDS. Recently, cases have been reported of patients colonized with atypical Mycobacteria who are only partially responsive to antibacterial treatment. It is thought that perhaps these cases represent a clinically different subset of patients that not only have underlying infection, but hypersensitivity disease as well, which may be responsive to concomitant treatment with oral corticosteroids.

Adrenal Cortex Hormones↗