Two patients who developed reversible renal failure during intermittent rifampicin therapy are described. Both had febrile reactions to rifampicin. The first was also found to have uraemia associated with swelling of the glomerular endothelial cells. The second developed tubular necrosis unassociated with haemolysis or shock. The pathogenesis of the renal lesion in these two patients, as revealed by light microscopy, immunofluorescence studies and electron microscopy, is discussed.

Acute Kidney Injury↗

PubMedDate not supplied

Cutaneous cryptococcosis.

A fatal case of cutaneous cryptococcosis in a Chinese patient suffering from non-Hodgkin's lymphoma is reported.

Antineoplastic Agents↗