Search PubMed⌕ Search

Biomedical subjects

R Y Tang

Publications and source records attributed to R Y Tang.

15 recordsLinked to original sources
PubMed1999

Sputum induction to improve the diagnostic yield in patients with suspected pulmonary tuberculosis.

OBJECTIVE: To evaluate the utility of sputum induction in the large-scale tuberculosis control program. METHODS: Prospective study on sputum induction for improving the diagnostic yield of pulmonary tuberculosis, and estimation of the direct costs for sputum induction. RESULTS: Of 1,648 tuberculosis suspects with poor or absent sputum production, induced sputum was smear-positive in 558 patients (353 previously smear-negative, 97 inadequate sputum and 108 unproductive). The direct cost per induced sputum was US $0.37. CONCLUSION: Sputum induction is an effective, low-cost, and simple technique for improving the smear-positive case detection rate in a tuberculosis control program.

Adolescent↗
PubMed1997

Construction of a cell-based high-flux assay for the rev protein of HIV-1.

The Rev of HIV-1 is essential for the replication of the viruses and is therefore a very attractive target for the development of antiviral drugs. To establish a cell-based high-flux assay system for random screening of Rev inhibitors, cells carrying both the Rev-expressing gene and a Rev-inducible SeAP gene were generated by permanent transfection. SeAP produced by these cells was 5-10-fold higher than that synthesized by cells not carrying the Rev gene. Northern blot analysis demonstrated that the increase in SeAP was due mainly to an increase in SeAP transcripts, indicating the effect of Rev proteins synthesized by the transfected cells. The assay system reported in this study should be useful for screening novel Rev inhibitors.

Alkaline Phosphatase↗
PubMed1991

[Relationship between inhibitory action of tanshinone on neutrophil function and its prophylactic effects on myocardial infarction].

In isoprenaline-induced myocardial infarction in rabbits, the circulating neutrophils (neu) were in an activated state. tanshinone (tan, ig) suppressed the neu functions (acid-phosphatase release, adhesiveness, and phagocytosis) dose-dependently and reduced myocardial necrosis concomitantly. There was a positive correlation between neu functions and myocardial necrosis. In addition, tan caused an obvious decrease in content of lipoperoxide malondialdehyde in serum and myocardium, an increase in superoxide dismutase activity, an inhibition of leukocytic infiltration, and a production of prostaglandin E2 in myocardium. These effects were also related closely to the suppression of neu functions. Anti-inflammatory drug dexamethasone was used as control and had similar effects on Neu functions and myocardial infarction. It is suggested that the prophylactic effects of tan on myocardial infarction may result from the inhibition of circulating neu functions.

Abietanes↗
PubMed1989

[Effects of tetrandrine on vascular permeability and neutrophil function in acute inflammation].

The effects of tetrandrine (Tet) on vascular permeability and neutrophil (Neu) functions in carrageenin induced subcutaneous air pouch inflammation in rats were studied. It was found that the vascular permeability, Neu emigration, beta-glucuronidase (beta-G) release and superoxide anion (O2-) generation were increased in the carrageenin induced inflammation. The vascular permeability, Neu emigration, beta-G release and O2- generation were suppressed by Tet ip (20, 40, 100 mg/kg), but the intracellular superoxide dismutase (SOD) activity and the cAMP level in Neu were increased by the same dose of Tet. The results indicate that Tet inhibits prostaglandin synthesis and scavenges free radicals. The mechanism of the inhibitory effects of Tet on Neu functions may be related to the increases in SOD activity and cAMP levels in Neu.

Alkaloids↗
PubMed1976

Role of the general dentist in maxillofacial prosthetics.

Care of oral cancer patients requires the opinions and coordinated efforts of various consultants or therapists functioning as a multidisciplinary team to treat individual patients' physical, social, and economic problems. The modern medical concept of total treatment of the patient must include dentistry. Every dentist with interest and training in the basic principles of maxillofacial prosthetics can offer invaluable assistance in the treatment of maxillofacial patients.

Dentures↗
PubMedDate not supplied

Polyurethane elastomer as a possible resilient material for denture protheses: a microbiological evaluation.

A polyurethane elastomer was microbiologically evaluated in vitro for its potential use in resilient denture liners. Specimens were immersed in suspensions of ten selected oral microorganisms; this was followed by viable cell counts at intervals during a 16-week period. Results indicated that the polyurethane neither supported the growth of the organisms nor was it degraded.

Candida↗