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Biomedical subjects

R Witmer

Publications and source records attributed to R Witmer.

At least 37 records · Page 2Linked to original sources
PubMed1982

Corneal endothelial changes in primary acute angle-closure glaucoma.

In 20 patients, corneal endothelium was examined by specular microscopy after acute angle-closure glaucoma, and before any surgical treatment in order to assess possible damage during pressure induced abnormal hydration of the cornea. The mean intraocular pressure was elevated to 55 mm Hg and had lasted, on an average, 47 (5--192) hours. The mean endothelial cell density in the affected eye was 1534 and in the nonaffected fellow eye 2243 cells/mm2 (mean decrease 33%, P = 0.002). The amount of cell loss correlates with the duration of the intraocular pressure increase. Thirty-five percent of these patients presented a bilateral cornea guttata. This high incidence of endothelial dystrophy was confirmed in a retrospective specular microscopic study in 20 patients with a history of unilateral acute angle-closure glaucoma. The decreased number of endothelial cells after acute angle-closure glaucoma frequently combined with bilateral cornea guttata, accounts for the corneal degeneration in these patients following a later cataract extraction.

Aged↗
PubMed1981

[Keratoplasty].

The different indications for penetrating keratoplasty are discussed on the basis of the clinical results of the past five years. Keratoconus is the most important group, followed by other corneal dystrophies, metaherpetic keratitis, graft failures and corneal scars. The results are very good in the first two groups, much less so in the last two. Eyes with repeated keratoplasty have a bad prognosis. One-half of the regrafts become cloudy. The most important postoperative complications, such as wound dehiscence, glaucoma, allograft reaction and anterior synechias are discussed.

Corneal Diseases↗
PubMed1981

[Astigmatis following perforating keratoplasty in keratoconus patients (author's transl)].

Earlier studies of successful keratoplasties in keratoconus patients showed that despite clear healing of transplants, a high degree of regular astigmatism very often results. A series of 28 eyes operated with a double running corneal suture is critically analyzed. It can be seen that, even using this suture technique, the final result after removal of the two sutures is still accompanied by a high degree of astigmatism. The cause of the residual astigmatism is thus probably due to the weakness of the peripheral corneal rim.

Astigmatism↗
PubMed1980

[Juvenile nevoxanthogranuloma of the iris].

Juvenile Xanthogranuloma of the iris is a rare but benign disease of infants. The iris is swollen and of yellowish color, there are exsudates in the anterior chamber and occasionally spontaneous hyphema may occur. Secondary glaucoma with edema of the corneal epithelium and hydrophthalmus are often seen. Treatment consists in topical application of steroids, sometimes combined with pressure-lowering medication.

Corneal Diseases↗
PubMed1978

Clinical implications of aqueous humor studies in uveitis.

We studied the serologic findings in serum and aqueous humor samples from 693 cases of uveitis. Specimens were tested for the presence of humoral antibodies against tuberculosis, toxoplasmosis, antistreptolysin-O, herpes simplex and herpes zoster viruses, mumps virus, and adenovirus. Serologic analyses rarely indicated tuberculous or streptococcal infections, but frequently showed toxoplasmosis and viral diseases.

Antibodies↗
PubMed1978

[Specular microscopy of the corneal endothelium (author's transl)].

Specular microscopy enables the examination of the endothelium of the isolated and perfused cornea. It is of great help in evaluating donor material in an Eye Bank. The in vivo observation and microphotography of the corneal endothelium makes it possible to detect early degenerative, traumatic surgical and other pathological changes of the monolayer.

Adult↗