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Biomedical subjects

R Witek

Publications and source records attributed to R Witek.

At least 19 recordsLinked to original sources

[Obstruction of the small intestine caused by malignant lymphoma].

Primary malignant tumors of the small intestine are a rare finding, not thought to be a likely case of intestinal obstruction. A case is reported of a patient presenting with chronic abdominal pain, apparently due to adhesions and a postoperative hernia (already after its repair). On laparotomy two tumors of the small, intestine were found obstructing its lumen, diagnosed histopathologically as primary malignant lymphoma.

Biopsy↗

[Atypical case of retroperitoneal paraganglioma parasympaticum coexisting with recurrent bleeding from upper gastrointestinal tract].

The authors report a case of 47 years old male who was treated for 1,5 year because of recurrent bleedings from upper GIT. Performed examinations showed the presence of retroperitoneal paraganglioma parasympaticum with multiple metastases in bones. A Zollinger-Ellison syndrome was suspected. The final correct diagnosis was established at last microscopically after surgical excision of the specimens.

Bone Neoplasms↗

[Methanol poisoning in the Tarnów region in the years 1982-1992].

In the paper five cases of methanol poisoning in Tarnów region treated with hemodialysis are presented and discussed. Despite a high dose of ingested alcohol and high levels of blood methanol concentrations and severe metabolic acidosis all treated patients survived and fully recovered.

Adult↗

[Acute ethylene glycol poisoning in the Tarnów region in the years 1982-1993].

The paper presents 15 causes of severe ethylene glycol poisoning in Tarnów region in the years 1982-1993. In the treatment haemodialyses as well as acidosis balancing and aethanol administration as an antidotum were preferred. Acute renal failure was observed in 73% of poisoned patients and mortality rate was 53%. The causes of treatment failure were: high ingested poison dose, too long time between poisoning and administration to hospital (and introduction of an appropriate treatment), critical clinical condition and severe metabolic acidosis.

Acute Kidney Injury↗

Studies on antifungal properties of phenol complexes with secondary amines. 3. The antimycotic activity of the complex of 2,4,5-trichlorophenol with dicyclohexylamine in the treatment of experimental mycosis.

2,4,5-trichlorophenol complexed with dicyclohexylamine was used for treatment of experimental mycosis. From the mycological and clinical evaluation the conclusion can be drawn that the effect of phenol in lipophilic ointment is comparable to that of clotrimazole (Canesten-cream "Polfa" licensed by Bayer) with the statistical significance p less than 0.001.

2,4,5-Trichlorophenoxyacetic Acid↗

The cytotoxic action in vitro of catalytically sulphurated unsaturated fatty acids on Ehrlich's ascites cancer and normal peritoneal exudate (leucocytes).

Diethanolamine salts of the catalytically sulphurated oleic acid (X-303/1) and of the catalytically sulphurated fatty acids isolated from linseed oil (X-303/2) were found to exhibit a strong cytotoxic in vitro activity against Ehrlich ascites cancer cells with minimal cytotoxic effect on normal cells (leukocytes) of the peritoneal exudate in rabbits.

Animals↗

[In vivo antimycotic effect of topically applied morpholine (author's transl)].

The effect of morpholine in the cure of experimental mycosis caused by Trichophyton mentagrophytes var. granulosum was studied. In all experiments the ointment or gel containing 10% morpholine. The liberation constant of the ointment and gel was k = 1.243 x 10(--1) x k(--1) and k = 3.713 x 10(--1) x k(--1) respectively. After treatment with the ointment or gel on the guinea pig skin, a cure of mycosis was observed. The antimycotic effect of morpholine was demonstrated in histopathological, mycological and clinical study. The effect of morpholine was compared with cream Canesten "Polfa".

Administration, Topical↗