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Biomedical subjects

R Widmer

Publications and source records attributed to R Widmer.

29 records · Page 2Linked to original sources
PubMed1987

Adjuvant intravesical chemotherapy of superficial bladder cancer with monthly doxorubicin or intensive mitomycin. A comparison of two consecutive series.

120 patients with the first occurrence of TNM stage Ta or T1 bladder carcinoma were given adjuvant intravesical treatment in 2 consecutive series. The first 60 received doxorubicin monthly for 6 months, then on the 9th and 12th month following surgery. The second series was given mitomycin weekly for 2 months, then monthly to the end of the first year. Median follow-up is 48 months in the first series and 15 in the second. In the doxorubicin group, 28 patients had recurrences. The recurrence rate is 1.86/100 patient-months. Seventeen of these first relapses occurred within the first year. In the 'intensive' mitomycin series, where 36 patients were observed for 12 months or more, 3 relapsed. The recurrence rate to date is 0.35. The relapse-free survival probability at 12 months is 75% in the first series and 93% in the second. Treatment was stopped due to toxicity in 4 patients in the doxorubicin group and in 10 of the mitomycin group.

Administration, Intravesical↗
PubMedDate not supplied

Anxiety in family practice.

The time course of patient initiated visits, somatic, functional, and other medical complaints was studied in a group of 58 patients from a family practice who had been diagnosed and treated for anxiety. The findings were contrasted with two other groups of patients from the same practice: 101 depressives and 101 controls. Results indicate that the anxiety patients differed markedly from the depressives in having a very short-lived episode of anxiety or somatic complaints in contrast to depressives' much longer history of somatic and functional complaints which appeared to precede by months the diagnosis of depression. The findings suggest that the anxiety patients in this practice either had a qualitatively different condition from the depressives, or possibly suffered from a short-lived and unrecognized depression.

Anxiety Disorders↗