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Biomedical subjects

R Wells

Publications and source records attributed to R Wells.

At least 145 records · Page 8Linked to original sources

Normal versus abnormal genital findings in children: how well do examiners agree?

In order to determine how well medical examiners agree on the significance of certain anogenital findings in children, preselected colposcopic photographs of the anogenital area of 16 patients were shown to 170 medical examiners (82% pediatricians) who were blinded as to the history on each patient. Findings rated most frequently as being suggestive or indicative of penetrating injury included immediate anal dilatation with no stool present (85%), hymenal transection (84%), marked narrowing of the hymenal rim with notching (81%), and a posterior fourchette scar (75%). The agreement between the participants and the experts on the abnormal cases (mean 81%) was significantly higher than on the normal cases (mean 71%, p < .001) and on genital findings (78%) than on anal findings (63%, p = .000). Higher experience level (more cases seen per month) was associated with significantly higher agreement between the participants and the experts on five of eight normal cases and two of four abnormal cases. Use of a colposcope was also associated with higher overall agreement with the experts (74% vs. 44%, p < .0001).

Anal Canal↗

Family stroke education.

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Cerebrovascular Disorders↗

A micropuncture study of the handling of calcium by the rat parotid.

The handling of Ca by the rat parotid gland was investigated using micropuncture, microperfusion, and microanalytical techniques. Concentrations of Ca were measured in salivary fluid from intercalated, lobular and main ducts, and net transductal fluxes of Ca and water were calculated during stimulation of secretion with acetylcholine, pilocarpine, and DL-isoproterenol.

Acetylcholine↗

Hantavirus pulmonary syndrome in a Chilean patient with recent travel in Bolivia.

A case of hantavirus pulmonary syndrome (HPS) was serologically confirmed in a critically ill patient in Santiago, Chile. The patient's clinical course had many similarities to that of other HPS patients in North and South America but was complicated by acute severe renal failure. The patient's history included self-reported urban and probable rural rodent exposure during travel in Bolivia. Comparison of a viral sequence from an acute-phase serum sample with other known hantaviruses showed that the hantavirus nucleic acid sequence from the patient was very similar to a virus recently isolated from rodents associated with HPS cases in Paraguay.

Adult↗

Spotlight on AIDS.

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Acquired Immunodeficiency Syndrome↗