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Biomedical subjects

R Walker

Publications and source records attributed to R Walker.

At least 451 records · Page 25Linked to original sources

Serum creatine phosphokinase levels in pigs reacting abnormally to halogenated anaesthetics.

Serum levels of creatine phosphokinase (CPK) were estimated in pigs. Among those known to react abnormally either to halothane alone or to halothane and suxamethonium most had very high levels of CPK. Twenty-four hours after five minutes' anaesthesia with halothane and oxygen a sustained, pronounced rise in the serum CPK occurred in some pigs-principally but not exclusively in the abnormal reactors. Estimation of the serum level of CPK may be a useful screening test for an abnormal hyperpyrexial response to halothane.

Anesthesia, Inhalation↗

Pulmonary and circulatory adjustments determining the limits of depths in breathhold diving.

Data on pulmonary gas exchange were collected in breathhold dives to 90 feet in a tank and in open-sea breathhold dives to depths of 217.5 and 225 feet. Thoracic blood volume displacements were measured at depths of 25, 50, 90, and 130 feet, by use of the impedance plethysmograph. The open-sea dives were carried out with an average speed of descent of 3.95 feet per second and an average rate of ascent of 3.50 feet per second. End-dive alveolar oxygen tensions did not fall below 36 millimeters of mercury, while alveolar carbon dioxide tension did not rise above 40 millimeters of mercury except in one case. These findings indicate that for diver Croft, who has unusual lung capacity, neither hypoxia nor hypercapnia determined the depth limits under those conditions. At depths of 90 and 130 feet blood was forced into the thorax, amounting to 1047 and 850 milliliters respectively.

Adaptation, Physiological↗

The Lieutenant.

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Blood Banks↗