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Biomedical subjects

R Walker

Publications and source records attributed to R Walker.

At least 415 records · Page 23Linked to original sources
PubMed1977

The CAP blood bank comprehensive survey program--1975.

The 1975 CAP Comprehensive Blood Bank Survey Program showed that the ABO and Rh typings were again at an excellent level of performance. What few errors still occurred were at least partially explained by a study that showed that many of these errors were directly traceable to clerical mistakes; many, in fact, were due to a complete failure to submit an answer. Antibody detection was very good when the antibody was strong, but lower levels of performance were attained when the antibody was weak. Low performance was also achieved with a cold-reacting anti-I, but here the difficulty was found to be more a lack of agreement on terminology of the antibody rather than a failure to demonstrate it. A study was performed to see whether the participants that were late in sending in the answer sheets had a higher error level than those that were not, but no difference was found. Finally, the preliminary results regarding the accuracies of various methods of antibody screening are presented. Although there was a statistically significant difference in the results obtained with the different methods, the study does not involve enough antibodies at this time to be valid, and therefore it will be continued.

ABO Blood-Group System↗
PubMed1975

The effects of Staphylococcus aureus and Klebsiella pneumoniae peritonitis in mice exposed to normal and hypoxic conditions on red cell oxygen transport function.

Normal mice exposed to 10% oxygen concentration developed a slight but statistically significant decrease in blood pH and a slight statistically insignificant decrease in red cell 2,3-DPG. Mice that were infected intraperitoneally with Staphylococcus aureus or Klebsiella pneumoniae and exposed to 20% oxygen developed acidosis, hemoconcentration, and decreased red cell 2,3-DPG levels. When mice with acute bacterial peritonitis were exposed to 10% oxygen concentration they likewise developed significant acidosis and hemoconcentration, but their reduction in red cell 2,3-DPG was not as great as that in the similarly infected mice exposed to 20% oxygen concentration.

Animals↗