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Biomedical subjects

R W Zabel

Publications and source records attributed to R W Zabel.

24 records · Page 2Linked to original sources
PubMed1988

Mycobacterium chelonei keratitis in a soft-contact-lens wearer.

A 29-year-old woman who had successfully used extended-wear soft contact lens for 7 years was found to have a corneal ulcer due to Mycobacterium chelonei. Unique to this presentation was the lack of a history of severe corneal trauma, prior surgery or immunocompromised tissue. Despite in-vitro resistance of the organism to amikacin sulfate, topical therapy with this antibiotic led to a complete cure without the need for surgical intervention.

Administration, Topical↗
PubMed1988

Intraocular pressure reduction prior to retrobulbar injection of anesthetic.

Following the retrobulbar injection of anesthetic, the application of a mechanical device to lower the intraocular pressure will produce a rise in intraocular pressure that may be sufficient to compromise ocular perfusion. To increase the margin of safety for ischemic damage, a mechanical means of intraocular pressure reduction (Superpinkie) was applied prior to, rather than following, the retrobulbar injection of anesthetic. The study group consisting of 20 patients receiving the compression-injection sequence had a mean preoperative pressure of 4.70 mm Hg, while a control group of 20 patients receiving the injection-compression sequence had a mean preoperative pressure of 2.25 mm Hg. The proposed compression-injection method was well tolerated by the patients and attained surgically adequate anesthesia, akinesia, and ocular opening pressures. In selective cases, the compression-injection technique for the delivery of retrobulbar anesthesia may offer a means of better maintaining ocular perfusion and thereby lessening the risk of vascular compromise.

Anesthesia, Local↗
PubMed1988

Infectious crystalline keratopathy.

Crystalline deposits developed in the anterior third of the stroma in a 60-year-old woman. The deposits resolved only after aggressive treatment with intravenously given penicillin and topical erythromycin and vancomycin hydrochloride. Review of reported cases indicated that infectious crystalline keratopathy is caused by chronic colonization of the stroma by bacteria, usually streptococci of the viridans group. Local tissue trauma, concomitant use of topical corticosteroids, an intact overlying epithelium and use of a bandage-type soft contact lens are factors in the development of the infection. Patients with crystalline formations in this setting should undergo early lamellar biopsy for histologic examination, culture and sensitivity testing, followed by aggressive therapy with appropriate antibiotics.

Administration, Topical↗
PubMedDate not supplied

Topography and raytracing analysis of patients with excellent visual acuity 3 months after excimer laser photorefractive keratectomy for myopia.

We performed topography and raytracing analysis 3 months after surgery on five consecutive eyes of five patients, which had excimer laser photorefractive keratectomy for myopia. Three of the five eyes had uncorrected postoperative visual acuity of 20/20 or better. Two eyes had an uncorrected vision of 20/40. In three of five eyes, the area of excimer ablation was centered within 1.0 mm of the optical axis. Three other eyes showed decentration that ranged from 1.1 to 1.5 mm. The range of surface power seen within 2 mm of the central keratoscope ring was as follows: patient CK = 37.50 to 39.50 diopters; patient CA = 40.50 D to 44.80 D; patient CW = 37.90 D to 42.20 D; patient AC = 35.50 D to 39.00 D; patient DT = 34.50 D to 41.40 D. Topography patterns differed from eye to eye. A raytracing program modeled refraction of 20/80 and 20/20 "E" of 100%, 50%, 25%, 12.5% and 6.25% contrast through all measured points on the central 10 keratoscope rings of the five postoperative corneas. The five computer-derived images were ranked subjectively according to the observed degree of image degradation by three observers. Two eyes showed discernible 20/20 E's even at the 12.5% contrast level. Little to no ghost image was seen. Two eyes showed degraded but discernible 20/20 letters at higher levels of contrast only. These eyes showed moderate ghost images that were most apparent in the high-contrast 20/80 letters. One eye showed poor resolution of the 100% contrast 20/20 letter and moderately severe ghost images.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMedDate not supplied

Myopic excimer laser keratectomy: a preliminary report.

Six patients underwent excimer laser refractive keratectomy for the correction of myopia. All eyes, with the exception of patient 6, who underwent a previous failed epikeratophakia procedure and subsequent removal of the lenticule, had normal baseline ophthalmologic evaluations and best corrected visual acuities of 20/25 or better. Spherical equivalents ranged between -5.50 and -12.00 diopters. Under topical and peribulbar anesthesia, the central corneal epithelium was removed. The delivery system of the laser was programmed to ablate corrections onto the central 5.0 mm of the cornea that would result in approximate emetropia. Moderate fluctuation of refractive and topographic parameters was noted during the period of epithelial healing and remodeling. At the 12th postoperative week, five of the corneas were clear on biomicroscopic evaluation with best corrected acuities of 20/20. The final patient, who was noncompliant in the use of topical corticosteroid therapy, developed a central, 2-mm opacity and resulting best corrected acuity of 20/40. Overall, the group demonstrated that myopic excimer laser photorefractive keratectomy is consistent with good wound healing, insignificant corneal scarring, a stable refractive correction, and excellent visual acuity.

Adrenal Cortex Hormones↗