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Biomedical subjects

R W Smith

Publications and source records attributed to R W Smith.

At least 145 records · Page 8Linked to original sources
PubMed1982

Activities of some enzymes of glucose metabolism in bovine liver and kidney cortex at three stages of lactation.

The activities (per g of tissue) of hexokinase, phosphofructokinase and pyruvate kinase were unchanged throughout lactation in liver and in kidney cortex. In both these tissues glucose 6-phosphatase activity decreased during late lactation. At the same time fructose diphosphatase activity increased in kidney cortex but not in liver. Activities of the pentose cycle dehydrogenases and of aspartate aminotransferase tended to increase in mid lactation. For most enzymes the activities at peak lactation were similar to those for dry, non-pregnant cows and there was no specific response of the gluconeogenic enzymes. Total hepatic contents of most enzymes tended to increase in mid lactation, but the changes were not clear cut and were the result of an increase in liver size.

Animals↗
PubMed1980

Communication failure in primary care. Failure of consultants to provide follow-up information.

In a two-physician general practive within 80 km of two university medical centers, there were 4,367 patient visits in six months, from which 233 referrals (5.3%) were made to consultants. All referred patients were accompanied by referral material and a request for follow-up information. The overall rate of receiving follow-up information was 62%. Private specialists provided substantially more follow-up information (78%) than either university-affiliated emergency rooms (48%) or university-affiliated specialty clinics (59%). Patients requiring continuing medical supervision from the referring physician also fared poorly: follow-up information for them was provided only 54% of the time. The timeliness and method of providing follow-up information were examined and believed to be satisfactory when follow-up information was returned.

Academic Medical Centers↗
PubMed1980

Stereotaxic occlusion of 22 consecutive anterior communicating artery aneurysms.

The authors review 22 consecutive cases of anterior communicating artery aneurysms treated by stereotaxic iron-acrylic occlusion. There was no mortality and no rebleeding in this series. The morbidity was low, and 16 of the 22 patients have returned to work. The patients whose aneurysmss could be treated transsphenoidally enjoyed the best outcome.

Acrylates↗
PubMed1979

Allergic hypersensitivity to neomycin. Relationship between patch test reactions and 'use' tests.

The prevalence of neomycin patch test sensitivity in the general population is approximately 1%. We describe the relationship between positive neomycin patch tests and clinical "use tests" with two antibiotic combinations (Neosporin G cream and Neosporin ointment). The neomycin use test was positive in seven of eight subjects with a strongly positive patch test, and in two of four subjects with a weakly positive patch test. A positive use test usually occurred earlier and was always more intense with the cream base. The use test reactions were usually mild even with continued application of the antigen. Use tests with commercial products may be helpful in evaluating the clinical relevance of positive patch tests.

Drug Hypersensitivity↗
PubMed1979

Allergic contact hypersensitivity to nickel, neomycin, ethylenediamine, and benzocaine. Relationships between age, sex, history of exposure, and reactivity to standard patch tests and use tests in a general population.

A study population of 1,158 paid adult volunteers was obtained. Prior to patch testing, a history of previous exposure to four allergens also was obtained. Prevalence of positive reactions to patch tests was nickel, 5.8%; neomycin, 1.1%; ethylenediamine, 0.43%; and benzocaine, 0.17%. Nine percent of women reacted to nickel compared with 0.9% of men. There was a strong correlation of nickel sensitivity with a history of pierced ears, earlobe rash, and jewelry rash. Ten of 12 neomycin-positive subjects used neomycin for one week or longer on an inflammatory dermatosis, compared with six of 36 age-, race-, and sex-matched controls. By history, 85% were exposed to benzocaine, 48% to neomycin, and 15% to Mycolog (ethylenediamine). Of 127 patients referred to clinics for evaluation of contact dermatitis, 11% yielded positive tests to nickel, 6.3% to neomycin, 3.1% to ethylenediamine, and 1.6% to benzocaine. Data obtained from testing contact dermatitis patients are not applicable to the general population.

Adult↗
PubMed1979

Scintiangiographic diagnosis of acute mesenteric venous thrombosis.

Scintiangiographic findings of prolonged mesenteric activity in a case of acute mesenteric thrombosis is described and 105 cases with abdominal scintiangiography are reviewed. Usual peak mesenteric blush occurred 5--15 sec after initial visualization of the aorta. Normal clearance of this activity was 15--30 sec. Future cases should confirm the importance of this observation in early diagnosis of mesenteric venous thrombosis.

Acute Disease↗